Chronic interstitial nephritis cyclosporine

Penicillins Proton pump inhibitors Chronic interstitial nephritis Cyclosporine Lithium Aristolochic acid Renal vasculitis, thrombosis, and cholesterol emboli ... 

Chronic interstitial nephritis Cyclosporine Lithium Aristolochic acid... 

Diabetic or HIV nephropathy, analgesic abuse nephropathy, cyclosporine nephropathy, and chronic interstitial nephritis... 

Cyclosporine and tacrolimus have dramatically enhanced the success of solid organ transplantation. Nephrotoxicity, however, remains a major dose-limiting adverse effect of both drugs. " Early acute hemodynamically-mediated renal insufficiency and delayed chronic interstitial nephritis have been observed (see section on chronic interstitial nephritis later in this chapter). ... 

Lithium, cyclosporine, and only a few other drugs have been reported to cause chronic interstitial nephritis, which is usually a progressive and irreversible lesion. Streptozotocin and other antineoplastic nitrosoureas also cause dose-dependent chronic interstitial disease. In addition, mesalazine, 5-aminosalicylic acid, and ifosfamide may cause chronic interstitial nephritis, which usually resolves promptly when drug use is discontinued. 

Balkan nephropathy is non-destructive and noninflammatory tubulointerstitial renal disease [69]. The changes are non-specific and in the chronic, sclerotic phase they may be quite similar to changes observed in other chronic interstitial diseases such as analgesic nephropathy [70], vascular nephrosclerosis [69] cyclosporine-induced nephropathy [71], radiation nephritis [72,73] and aging [72], intoxication with silicate, cadmium, lead, uranium [74], mycotoxin ochratoxin... 

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