Chromatography, general theory

D. L. Peterson and F. Helfferich, Towards a generalized theory of gas chromatography at high solute concentrations. J. Phys. Chem.,... 

Forssen, R and Fomstedt, T. General theory of indirect detection in chromatography. J. Chromatogr. A. 2006, 1126, 268-275. 

Blue Sepharose.CL-6B, firm literature of Pharmacia, Uppsala, Sweden Haff, L. A., Easterday, R. L. Cibacron Blue-Sepharose A tool for general ligand affinity chromatography, in Theory and Practice in Affinity Technoques, (ed. Sundaram, P. V., Eckstein, F.) Academic Press 1978... 

The separation techniques which collectively are called chromatography are probably the most widely used chemical separations in the laboratory. They have had a tremendous impact on the chemical sciences and finally upon society. The general theories, Chapter 14, and nine variations, Chapters 15 to 22, will be discussed in this subsection. 

V. V. Rachinskii, The General Theory of Sorption Dynamics and Chromatography, Consultants Bureau, New York, 1965 (English translation). 

The general theory of micellar electrokinetic chromatography represents a confluence of chromatographic and electrophoretic principles. The expressions for electrophoretic mobility under different separation conditions are summarized in Table 8.4 [161,162]. These relationships allow the determination of the critical micelle concentration and equilibrium distribution constants for solute-micelle association complexes under typical conditions for micellar electrokinetic chromatography [60-64,161-164]. These properties change significantly with the composition of the electrolyte solution, and are generally different to common reference values for pure water. 

Glueckauf E. (1949) Theory of chromatography VII. The general theory of two solutes following non-linear isotherms. Discuss. Faraday Soc., 7,12. 

In case of a stable and stationary chromatographic system, the derived general theory is certainly usable for calculating quantitatively uncertainties and detection limits in signal integrating methods like chromatography. However, an extensive analysis of the detector noise is required and the use of a computer with a data acquisition system and special software is inevitable. 

The general theory of countercurrent distribution is still of general interest since manual liquid-liquid extraction remains a common laboratory technique. In addition, countercurrent distribution models often provide a starting point for the explanation of separations by chromatography and continuous liquid-liquid extraction processes. A favorable feature of countercurrent distribution systems is that separations are completely predictable, once the solute distribution ratios and the phase ratio are known. 

It follows from the general theory of chromatography that the elution curve F(V) (chromatogram) of a uniform solute can be approximated by a Gaussian distribution function ... 

Belenkii, B. Vilenchik, L. General theory of chromatography. In Modem Liquid Chromatography of Macromolecules Joiunal of Chromatography Library Elsevier Amsterdam, 1983 Vol. 25,1 7. 

This present chapter will not focus on the statistical theory of overlapping peaks and the deconvolution of complex mixtures, as this is treated in more detail in Chapter 1. It is worth remembering, however, that of all the separation techniques, it is gas chromatography which is generally applied to the analysis of the most complex mixtures that are encountered. Individual columns in gas chromatography can, of course, have extremely high individual peak capacities, for example, over 1000 with a 10 theoretical plates column (3), but even when columns such as these are... 

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