Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Choline Citicoline

Citicoline (cytidinediphosphate-choline/CDP-choline 26) is an intermediate in the biosynthesis of acetylcholine. It has been extensively used for the treatment of neurodegenerative disorders associated with head trauma, stroke, brain aging, and AD. Studies in mice have indicated a protective effect of citicohne against memory impairment induced by adverse environments. A human study recruited 30 patients with mild to moderate AD in a double-blind, randomized and placebo-controlled clinical trial... [Pg.389]

Puglisi, G.,Fresta,M.,La Rosa, C., Ventura, C. A., Panic, A. M., and Mazzonne,A. (1992), Liposomes as potential drag carrier for citicoline (CDP-choline) and the effect of formulation conditions on encapsulation efficiency, Pharmazie, 47, 211-215. [Pg.512]

Citicoline (CDP-choline) is an intermediate in PtdCho biosynthesis. It has been used for the treatment of ischemic and head injuries (Andersen et al., 1999 Dempsey and Rao, 2003). It not only restores the concentration of PtdCho following ischemic injury by increasing PtdCho synthesis from diacylglycerol but also blocks the activation of CPLA2 activity (Adibhatla et al., 2002 Adibhatla and Hatcher, 2003). The... [Pg.237]

See other pages where Choline Citicoline is mentioned: [Pg.1624]    [Pg.1682]    [Pg.68]    [Pg.1624]    [Pg.1682]    [Pg.1624]    [Pg.1682]    [Pg.1624]    [Pg.1682]    [Pg.68]    [Pg.1624]    [Pg.1682]    [Pg.1624]    [Pg.1682]    [Pg.104]    [Pg.78]    [Pg.470]    [Pg.361]    [Pg.72]    [Pg.82]    [Pg.82]    [Pg.83]    [Pg.237]    [Pg.238]   


SEARCH



Citicoline

© 2024 chempedia.info