Thalidomide Chlorpromazine

Thalidomide enhances the sedative actions of alcohol, barbiturates, chlorpromazine, and reserpine (118), perhaps by additive effects on their several pharmaco-djmamic actions (196), although other mechanisms have been described (197). [Pg.3355]

Hydrogen sulfide Polychlorinated biphenyls Tri-o-tolyl phosphate Cisplatin Chlorpromazine Doxorubicin Thalidomide Valproic acid Botulinum toxin... [Pg.137]

Thalidomide s interactions with other dmgs have not been systematically addressed, except for lack of significant interaction with oral contraceptives and thalidomide s effect in enhancing the sedative effects of barbitnrates and alcohol and the catatoiuc effects of chlorpromazine and reserpine. Conversely, CNS stimnlants (snch as metham-phetamine and methylphenidate) connteract the depressant effects of thalidomide. [Pg.682]

Animal studies have shown an increase in CNS depressant activity when thalidomide was given with alcohol, barbiturates, chlorpromazine and reserpine. ... [Pg.664]

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