Chloroquine phosphate sulphate

Ampicillin sodium Amylobarbitone Betamethasone Betamethasone valerate Carbenicillin disodium Chloroquine phosphate Chloroquine sulphate Cemetidine Clofazimine Clofibrate Clonidine... 

Chloroquine Phosphate 566.6 Quinuronium Sulphate 671.8 Ergotoxine Esylate... 

The active component of many drugs, whether acid or base, is relatively insoluble and may present a problem in formulation. This is overcome by adding an acid to a base or vice versa the weight of the salt differs according to the acid or base component, i.e. chloroquine base 150 mg = chloroquine sulphate 200 mg = chloroquine phosphate 250 mg (approximately). Where there may be variation, therefore, the amount of drug prescribed is expressed as the weight of the active component, in the case of chloroquine, the base. 

Several 4-aminoquinolines have now been tested and hydroxychloroquine sulphate (Plaquenil XLV, R =Et, R =CH2-CH2-OH), a closely related derivative of chloroquine, is known to possess antirheumatic properties similar to those of chloroquine . Amodiaquine (Camoquin, XLVl, R=NEt2) also possesses activity but seems to be too toxic for routine use . . . However, the closely-related amopyroquin (Propoquin, XLVI, R=pyrrolidino) appears to possess desirable clinical activity without serious toxicity . Drugs of the 4-aminoquinoline type in most frequent use are chloroquine phosphate, 250-500 mg daily, chloroquine sulphate, 200-400 mg daily, and hydroxychloroquine sulphate, 400-600 mg daily . A striking feature of this therapy is that beneficial effects are often not apparent until... 

Orciprenaline Sulphate Trifluperidol Hydrochloride Ampicillin Sodium Disopyramide Phosphate Prednisolone Succinate Chloroquine Sulphate Guanoxan Sulphate Frusemide... 

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