Chloromethyl anilines

Chlorobenzene Producers Association (CPA), 270 p-Chlorobenzotrichloride, 39 Chlorobenzotrifluorides, 39 Chlorobromomethane, 39 Chlorodifluorobromomethane, 39 Chlorodifluoroethane, 39 Chlorodifluoromethane, 39 Chlorodiphenyl, 39 Chloroethanol, 39 2-Chloroethyl vinyl ether, 39 Chlorofluorocarbons, 39 Chloroform, 40 Chloromethyl anilines, 40 Chloromethyl ether, 40 Chloromethyl methyl ether, 40 2-(4-Chloro-2-methylphenoxy) propionic acid, 40 Chloromethyl phenyl isocyanate, 40... 

Chloromethyl)aniline hydrochloride reacts at 160°C with the stannic chloride complex of acetonitrile to give 2-methyl-3,4-dihydroquinazoline (see 1). The nitrilium salt 78 is presumed to be the intermediate. Yields were excellent when other aliphatic and aromatic nitriles were used. JV-Methyl-2-(chloromethyl)aniline gave 2-alkyl- or 2-aryl- 1,4-dihydroquinazolines in excellent yields.74... 

Amyl bromide [Pentane, 1-bromo-], 82 Aniline [Benzenamine], 122 Anilines, o-alkylation of, 15 Anisole [Benzene, methoxy-], 48 Amsyl chloride [Benzene, l-(chloromethyl)-... 

Carbomethoxybenzaldehyde, 100 Carbon disulfide, 57 Chlorine, 24 Chloroacetamide, 22 Chloroacetonitrile, 22 Chlorobenzene, 96 lra i-2-CHLOROCYCLOPENTANOL, 24 2-Chloroethyl benzoate, 11 Chloromethylation, 68 1-Chloromethylnaphthalene, 67, 68 Chlorourea, see Monochlorourea Choline, chloride benzoate, 10 Choline, iodide benzoate, 10 Cinnamaldehyde, 75, 77 Cleavage of tetrahydrofuran, 27, 33 Condensation, of aniline and triphenyl carbinol, 5... 

Methyl(phenylaminomethyl)diethoxysilane (AM-2) is prepared by the etherification of methyl(chloromethyl)dichlorosilane with anhydrous ethyl alcohol and subsequent amidation of the etherified product with aniline. 

At the stage of methyl(phenylaminomethyl)diethoxysilane amidation with aniline, the chlorine atoms in the chloromethyl radical are replaced with a phenylamine group, which forms... 

We should note that the reactor receives an excess of aniline, so that the amidation of methyl(chloromethyl)diethoxysilane is accompanied by the binding of released hydrogen chloride. When introducing aniline, one should keep a close watch on the temperature in the reactor, since the process takes place with the liberation of heat. After aniline has been introduced, the reactive mixture is heated to 135-140 °C within 2-3 hours and agitated at this temperature for 8-8.5 hours. After that reactor 6 is... 

Cs-X has also been used to promote the selective O-methylation of phenol with dimethyl carbonate. 2 N-Monomethylaniline was obtained in 93% yield by reacting aniline with dimethyl carbonate over a K-Y catalyst at 180°C (Eqn. 22.46). 3 The reaction of alcohols with chloromethyl ether over Na-Y gave the resulting methoxymethyl ethers in 70%-90% yields (Eqn. 22.47). 4... 

Azasilacyclopentanes are most conveniently prepared by the amidomercuration-demercuration of dimethyl(chloroalkyl)alkenylsilanes of the form (131) <87JOM(326)i59,85ZOB706). Thus, treatment of dimethyl(chloromethyl)vinylsilane (Ola, n = 0) or dimethyl(chloromethyl)allylsilane (131b, n = 1) with aniline in THF in the presence of mercury acetate, followed by reduction with sodium borohydride, afforded the azasilacyclopentanes (Ola), (132b). 

CHLOROMETHYL OXIRANE (106-89-8) C3H5CIO Highly flammable, polymerizable liquid. Forms explosive mixture with air [explosion limits in air (vol %) 3.8 to 21.0 flash point 69°F/21°C 88°F/31 °C autoignition temp 772 F/411 °C Fire Rating 3]. Reacts violently with water. Contact with elevated temperatures, contamination, strong acids, strong bases, metallic halides, aluminum, aluminum chloride iron(III) chloride and other chlorides of iron or zinc can cause explosive polymerization. Violent reaction with aniline, hypochlorite, isopropylamine, potassium ieri-butoxide (ignition), sulfuric acid. Mixtures with trichloroethylene forms explosive dichloroacetylene. Incompatible with aliphatic amines, alkaline earths, alkali... 

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