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N-Amyl bromide

Bromopentane. Proceed as for n-Amyl Bromide, but use 88 g. (108 ml.) of methyl n-propyl carbinol (2-pentanol), b.p. 118-5°. During the washing with concentrated hydrochloric acid, difficulty may be experienced in separating the acid layer this is overcome by adding a little water to decrease the density of the acid. Distil the purified product through a fractionating colunm some amylene passes over first, followed by the 2-bromopentane at 115-118° (120 g.). [Pg.279]

Elimination from iso-Propyl, sec.-Butyl, 2 n-Amyl, and 3 n-Amyl Bromides in Acidic and Alkaline Alcoholic Media. J. chem. Soc. (London) 1948, 2065-... [Pg.63]

Ammonolysis, 401 Ampoules, glass. 205 n-Amylamine, 413, 417 n-Amyl acetate, 383 -Amyl alcohol, 247, 249 n-Amylbenzene, 511, 517 n-Amyl borate, 305 n-Amyl bromide, 279 tao-Amyl bromide, 279 n-Amyl chloride, 273 tao-Amyl chloride, 273 tert.-Amyl chloride, 275 n-Amyl cyanide, 407, 408 Amylene, 239 n-Amyl fluoride, 272, 289 n-Amyl iodide, 288 n-Amyl nitrite, 302, 306... [Pg.1167]

As to the preparation of MAM, the exact same sequence was used, except for the employment of n-amyl bromide. The benzaldehyde crystallized from methanol with amp of79-80 °C, and formed amalononitrile derivative which was bright yellow and melted at 103-104 °C. The nitrostyrene, when pure, melted at 57-58.5 °C but proved very difficult to separate from the aldehyde. The final product, 4-(n)-amyloxy-2,5-dimethoxyamphetamine hydrochloride (MAM) was obtained by lithium aluminum hydride reduction in ether and melted at 125-127 °C. It was assayed at up to 16 milligrams, at which level there was noted a heaviness in the chest and head at the 2-hour point, but no cardiovascular disturbance and no mydriasis. This was called an inactive level, and no higher one has yet been tried. [Pg.414]

Chemical Name n-amyl bromide, 1-bromopentane, monobromopentane, pentyl bromide... [Pg.245]

A mixture of 340 ml. of ethanol and 147 g. (1.52 moles) of potassium thiocyanate is heated to reflux, and 157 g. (1.04 moles) of n-amyl bromide is added dropwise. Reflux is continued for 2 hours after completion of the addition of the bromide. Most of the ethanol is removed by distillation, and the residue is diluted with water and extracted with ether. The combined ethereal extracts are dried over calcium chloride, and the ether is removed by distillation. Fractional distillation of the residue at 16 mm. pressure gives an 85% yield of n-amyl thiocyanate, b.p. 90-91°. [Pg.29]

The alkyllithiums from the bromides listed below may be prepared in similar manner in the yields indicated n-propyl bromide, 78% n-amyl bromide, 81% and n-hexyl bromide, 77%. [Pg.74]

Tin diethyl-n-amyl bromide is obtained as a colourless, thick, unpleasant smelling oil, by adding the requisite quantity of bromine in ethyl acetate to tin triethyhn-amyl. [Pg.331]

C) Ammonolysis of Alkyl Halides. Place 20 ml of a saturated alcoholic solution of ammonia in methanol (90 per cent) in each of two test tubes. To the first add 2 g of n-amyl bromide, and to the second 2 g of each reaction mixture 20 ml of water, and separate the upper layer of amine (and imchanged halide). Test two drops of each product for amy-lene by shaking with 2 ml of 0.1% potassium permanganate or bromine water. Record the observations. Place the sample of amine in the proper bottle provided by the instructor for future study. [Pg.145]

D) Action of Alcoholic Alkali. Use alcoholic potassium hydroxide solution containing 30 g of the solid dissolved in 90 ml of 90 per cent methyl or ethyl alcohol. Place 3 ml of the alkali solution in each of three tubes. Add to seperate respective tubes 1 ml of n-amyl bromide, benzyl chloride. Shake gently for a minute, cork, label each tube, and set aside for the next laboratory period. If it is desired to observe the rate at which the halides react, examine after 30 minutes the extent of the reaction as judged by the amount of potassium halide formed. After 24 hours add 3 ml of water, shake, and allow to separate. Note the odor. With a clean dropper or pipette withdraw two drops from each and test with bromine water and dilute permanganate. n -Amyl bromide yields a considerable amoimt of ether, but little olefin. Benzyl chloride yields entirely carbinol. Put the contents of the three tubes into bottles provided by the instructor. [Pg.145]


See other pages where N-Amyl bromide is mentioned: [Pg.237]    [Pg.279]    [Pg.279]    [Pg.279]    [Pg.289]    [Pg.323]    [Pg.53]    [Pg.112]    [Pg.200]    [Pg.233]    [Pg.110]    [Pg.670]    [Pg.237]    [Pg.279]    [Pg.289]    [Pg.323]    [Pg.117]    [Pg.120]    [Pg.92]    [Pg.120]    [Pg.279]    [Pg.279]    [Pg.279]    [Pg.323]    [Pg.53]    [Pg.401]    [Pg.110]    [Pg.45]    [Pg.507]    [Pg.28]    [Pg.355]    [Pg.373]   
See also in sourсe #XX -- [ Pg.279 ]

See also in sourсe #XX -- [ Pg.279 ]

See also in sourсe #XX -- [ Pg.16 , Pg.41 ]

See also in sourсe #XX -- [ Pg.99 , Pg.203 ]

See also in sourсe #XX -- [ Pg.279 ]

See also in sourсe #XX -- [ Pg.279 ]

See also in sourсe #XX -- [ Pg.17 , Pg.58 ]




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