Chloroformates dichloromethyl

An alternative procedure used for large apparatus is to rinse the apparatus with a 5% solution of dichloromethyl silane in chloroform, followed by several rinses with water before baking the apparatus at 180°/2h (for glass) or drying in air (for plasticware). 

Diakyl carbamyl chlorides Diakyl aluminum hydrides Diborane Dibromoketone Dichloromethyl chloroformate Diphosgene Fuming nitric acid Gngnard reagents Hydrides nonvolatile... 

Furthermore they claimed that the dichloromethyhndolenine 17 could be converted into the quinohne 18 by hot ethanolic sodium ethoxide. They also reported other similar cases of ring expansion of the dichloromethyl bases, with loss of hydrogen chloride, on further treatment with sodium ethoxide (cf. ref. 67). They considered that chloroform acted like a simple alkyl halide giving jS-alkylation of the... 

Also reported as a mixture with Dichloromethyl chloroformate (C13-A018) Stannic chloride. 

C-Stoff Chloromethyl Chloroformate (70-90%) and Dichloromethyl Chloroformate (30-10%) Mixture Cl 3-A... 

Carbon tetrachloride. Chloroform, 2-Chlorophenol, Cyclohexanol, Cyclopentene, 1,1-Dichloroethylene, irans-l, 2-Dichloroethylene, IV.yV-Dimethylaniline, lV,lV-Dimethylformamide, 2,4-Dimethylphenol, 2,4-Dinitrotoluene, 1,4-Dioxane, 1,2-Diphenylhydrazine, Ethyl formate. Formaldehyde, Glycine, Methanol, Methylene chloride. Methyl formate, 2-Methvlphenol. Monuron, 4-Nitrophenol, Oxalic acid, Parathion, Pentachlorophenol, Phenol, l idine. Styrene, Trichloroethylene, Vinyl chloride Formylacetic acid, see cis-l,3-Dichloropropylene, irans-1,3-Dichloropropylene IV-Formylcarbamate of 1-naphthol, see Carbaryl Formyl chloride, see Chloroethane, Chloroform, sym-Dichloromethyl ether, ds-1,3-Dichloropropylene, irans-ES-Dichloropropylene, Methyl chloride. Methylene chloride. Trichloroethylene, Vinyl chloride lV-Formyl-4-chloro-o-toluidine, see Chlornhenamidine. 

Hydracrylic acid, see p-Propiolactone Hydrazobenzene, see Aniline Hydriodic acid, see Methyl iodide Hydrobromic acid, see Bromodichloromethane, Bromoform, Methyl bromide, Metobromuron Hydrochloric acid, see Alachlor. Aldrin, Benzyl chloride, a-BHC, p-BHC, Bis (2-chloroethyl) ether, Bis(2-chloroisopropyl) ether, Bromacil. Bromodichloromethane, Carbon tetrachloride, Chloroethane, Chloroform, o-Chloronitrobenzene. Chloropicrin, Chloroprene, p-Chloronitrobenzene, 2,4-D, see Dalanon-sodium. p.p -DDD, p,p -DDT, Dicamba. 1,1-Dichloroethane, 1,1-Dichloroethylene, fratts-l,2-Dichloroethylene, s/m-Dichloromethyl ether, 2.3-Dichloronitrobenzene. 3.4-Dichloronitrobenzene. 1,2-Dichloropropane, cis-1,3-... 

Surprisingly, there are only a few reports concerning the action of carbenes on azepines. A-ethoxycarbonyl-1//- azepine and dichlorocarbene, generated by the action of 50% potassium hydroxide on chloroform, furnish the trans -trishomoazepine (136 R1 = R2 = Cl) in 35% yield. Under similar conditions the 2,3- and 4,5-homoazepines yield the trans homoazepines (136 R1 = Cl, R2 = H and R1 = H, R2 = C1 respectively). From a careful study of the addition of dichlorocarbene, generated by thermal decomposition of (dichloromethyl)phenylmercury, it is concluded that carbene addition to the 1H-azepine takes place sequentially in the order C-4—C-5, C-2—C-3 and C-6—C-7 (74JOC455). 

The dichloromethyl derivative 20 is isolated (10%) from 3,4,5-trimethyI-pyrazole and chloroform in the presence of sodium ethoxide generation of dichlorocarbene by thermolysis of sodium trichloroacetate does not give any 4/Z-pyrazole.30 The same product is formed, in lower yield, using chloroform and base with a phase-transfer catalyst.31... 

Vilsmeier reaction), CICHOMe (from dichloromethyl methyl ether/titanium(iv) chloride), CC12 (from chloroform/sodium hydroxide, Reimer-Tiemann reaction), and 1,3-dithiane. 

Oxo-l//-2-henzotellurin (Isotellurocoumarin)3 2.9 g (10 mmol) of 2-(2 -chlorocarbonylphenyl)-ethenyl methyl tellurium and 100 mg of anhydrous zinc chloride are dissolved in 10 ml of dichloromethyl methyl ether and the mixture is kept overnight at 20°. The ether is evaporated and 50 ml of dry dichloromethane are added to the residue (the carboxylic acid chloride). This solution is cooled to — 80° and 1.33 g (10 mmol) of aluminum chloride are added with efficient stirring. The mixture is allowed to warm to 20°, it is then poured into 100 ml of ice/water. the mixture is extracted with chloroform, the extract is dried, and evaporated. The residue is recrystallized from hexane yield 0.77 g (30%) m.p. 83°. 

The direct reaction of (trichloromethyl)chlorosilanes was applied under the same reaction condition described in the direct reaction of elemental silicon with (dichloromethyl)chlorosilanes above. In this reaction, an admixed gases of hydrogen chloride and 40 wt% (trichloromethyl)chlorosilanes in toluene injected using a syringe pump in pre-heater zone was fed into a reactor charged with elemental silicon (90%) and copper catalyst (10%) (Fig. 1). This reaction afforded no tetrakis (chlorosilyl)methane instead, tris(silyl)methanes and bis(silyl)methanes were obtained, which were the same products derived from the reactions of (dichloromethyl)chlorosilanes or chloroform, and (chloromethyl)chlor-osilanes or methylene chloride, respectively. This result may be rationalized by decomposition of (trichloromethyl)chlorosilanes to (dichloromethyl)-chlorosilanes and (chloromethyl)chlorosilanes on silicon-copper contact mass during the reaction, followed by reaction with elemental silicon to afford the products or the decomposition tetrakis(silyl)methane products.16... 

Regioselective reaction of phenols. Reaction of phenols with chloroform in aqueous alkaline solution catalyzed by P-cyclodextrin results in virtually complete attack at the para-position by dichlorocarbene to give, after hydrolysis, 4-hydroxybenzaldehydes. If the para-position is substituted, 4-(dichloromethyl)-2,5-cyclohexadienones are obtained as the major product. The selectivity results from formation of a ternary complex from P-cyclodextrin, chloroform, and the phenol. ... 

Ethyl dichloroarsine. Dichloromethyl ether Trichloromethyl chloroformate Chloropicrin... 

The mixture of monochloromethyl chloroformate with dichloromethyl chloroformate, used in 1915 by the Germans under the name of K-Stoff," and later also by the Allies, especially the French, by whom it was called " Palite."... 

Dichloromethyl chloroformate reacts with cold potassium iodide, liberating iodine ... 

Ferric chloride and anhydrous aluminium chloride decompose dichloromethyl chloroformate slowly at ordinary temperatures and rapidly at 80° C., forming a mixture of carbon dioxide and chloroform ... 

Aniline in aqueous or benzene solution reacts with dichloromethyl chloroformate to give diphenylurea and formanilide according to the equation ... 

Dichloromethyl chloroformate is less irritant than the preceding compound, but more toxic. Its limit of insupportability is 75 cu. mm. per cu. m. (Flury). 

Identification of Dichloromethyl Chloroformate. On treating dichloromethyl chloroformate with water or an alkaline solution it decomposes according to the following equation ... 

Identification of Trichloromethyl Chloroformate. This substance may. be identified by its reaction with an aqueous solution of aniline (3 100). Like phosgene and dichloromethyl chloroformate, a white crystalline precipitate of diphenyl urea forms, which may be confirmed by microscopic examination (rhombic prisms) or by a determination of its melting point (236° C.). 

Determination of Dichloromethyl Chloroformate. The sample to be examined is treated with sodium hydroxide and the volume of carbon monoxide evolved is measured. 

I gramme-molecule of dichloromethyl chloroformate, the amount of the latter present in the sample may be calculated ... 

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