2- Chlorobenzylidene malononitrile

Chlorobenzene was not mutagenic in a variety of bacterial and yeast assays. Existing data suggest that genotoxicity may not be an area of concern for chlorobenzene exposure in humans. [Pg.147]

Although the odor of chlorobenzene is pronounced and unpleasant, it is not sufficient to give warning of hazardous concentrations. [Pg.147]

The 2003 threshold limit valuetime-weighted average (TLV-TWA) for chlorobenzene is 10 ppm (46mg/m ) with an A3-confirmed animal carcinogen with unknown relevance to humans designation. [Pg.147]

Kluwe WM, Dill G, Parsings A, et al Toxic responses to acute, subchronic and chronic oral administrations of monochlorobenzene to rodents. J Toxicol Environ Health 15 745-767, 1985 [Pg.147]

Nair RS, Barter JA, Schroeder RE, et al A two generation reproduction study with monochlorobenzene vapor in rats. Fundam Appl Toxicol 9 678-686, 1987 [Pg.147]

Chloroacetophenone (phenacyl chloride) Chlorbenzene (monochlorobenzene) o-Chlorobenzylidene malononitrile (OCBM) Chlorobromomethane/bromochloromethane 2-Chloro-l, 3-butadiene, see p-Chloroprene Chlorodiphenyl (42% chlorine)... [Pg.374]

Detailed Facts About Tear Agent o-Chlorobenzylidene Malononitrile (CS). Aberdeen Proving... [Pg.426]

Synonyms CS OCBM chlorobenzylidene malononitrile 2-chloro-benzylidene malonon-itrile... [Pg.147]

Toxicology. o-Chlorobenzylidene malononitrile (CS) aerosol is a potent lacrimator and upper respiratory irritant. [Pg.147]

The 2003 ACGIH ceiling-threshold limit value (C-TLV) for o-chlorobenzylidene malononitrile is 0.05ppm (0.39mg/m ) with a notation for skin absorption. [Pg.148]

Punte CL, Owens EJ, Gutentag PJ Exposure to or o-chlorobenzylidene malononitrile. Arch Environ Health 6 366-374, 1963... [Pg.148]

BallantyneB, Swanston DW The comparative acute mammalian toxicity of 1-chloroace-tophenone (CN) and 2-chlorobenzylidene malononitrile (CS). Arch Toxicol 40 75-95, 1978... [Pg.148]

Wild D, Eckhardt K, Harnasch D, et al Geno-toxicity study of CS (ottZ o-chlorobenzylidene-malononitrile) in Salmonella, Drosophila and mice. Arch Toxicol 54 167-170, 1983... [Pg.148]

Marts TC, Colgrave HF, Cross NL, et al A repeated dose study of the toxicity of inhaled 2 -chlorobenzylidene malononitrile (CS) aerosol in three species of laboratory animal. Arch Toxicol 52 183-198, 1983... [Pg.148]

Comparative Acute Mananalian Toxicity of 10-Chioro-5, lQ-dihydrophenarsa ine (DM7, Chloroacetophenone (CN), 2-Chlorobenzylidene Malononitrile (CS), and Oiben (b,f](1,4Joxazepine (CR) ... [Pg.142]

Holland, P. and White, R.G. The cutaneous reactions produced by o-chlorobenzylidene malononitrile and w-chloroacetophenone when applied directly to the skin of human subjects. Br. J. Dermatol.86 150-154, 1972. [Pg.168]

Shmunes, E. and Taylor, J.S. Industrial contact dermatitis. Effect of the riot control agent ortho-chlorobenzylidene malononitrile. Arch. Dermatol. 107 212-216, 1973. [Pg.170]

Mesilaakso, M., Analysis of the 1II and 13C H NMR spectral parameters of the tear gases a-chloroacetophenone, dibenz[b,f] [ 1,4]oxazepine, and 2-chlorobenzylidene malononitrile, Magn. Reson. Chem., 34, 989-994 (1996). [Pg.349]

Two chemists, Carson and Stoughton (1928), synthesized 2-chlorobenzylidene malononitrile (CS) however, it was not adopted by the military as an official RCA until 1959. As a more chemically stable compound and having a greater potency with less toxicity than CN, it gradually replaced CN as the preferred RCA. CS was widely used during the Vietnam War to flush the Viet Cong out of the... [Pg.153]

FIGURE 12.5. Chemical structure and physicochemical properties of ortho-chlorobenzylidene malononitrile (CS). [Pg.158]

Blain, P.G. (2003). Tear gases and irritant incapacitants 1-chloroacetophenone, 2-chlorobenzylidene malononitrile and dibenz[B,F]-l,4-oxazepine. Toxicol. Rev. 22 100-10. [Pg.171]

Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...