5- Chloro-8-quinolyl

The 5-chloro-8-quinolyl group can also be activated with CUCI2 under anhydrous conditions and used in triphosphate formation. ... 

Chloro-8-quinolyl protecting group in oligonucleotide synthesis ... 

Whereas cyclization of 2-(3-chloropropionamido)quinolines (210) afforded 2,3-dihydro-l//-pyrimido[l,2-a]quinolin-3-ones (211), an attempted thermal cyclization of ethyl 3-[(2-quinolyl)amino]propionate (212) gave only 2-amino-6-chloro-4-phenylquinoline-3-nitrile (73YGK313). 

Cyclization of ethyl yV-(2-quinolyl)malonamates (213) in a mixture of polyphosphoric acid and phosphoryl chloride gave 3-chloro-l W-pyrimido-[l,2-a]quinoline-l-ones (214) (74MIP1 84S152 95MI1). 

Schiff base 293 with dichlorocarbene, prepared from chloroform and potassium hydroxide in situ, in the presence of benzyltriethylammonium chloride afforded 2-chloro-3-phenyl-l //-pyrimido[l, 2-a]quinolin-l-one (294), l-chloro-2-phenylimidazo[l,2-a]quinoline, and l-(l-quinolyl)-2,2-dichloro-3-phenylaziridine in 5%, 8%, and 6% yields, respectively (91KGS810). 

For non-steroidal antiinflammatory carboxylic acids such as mefenamic acid" or A(-(7-chloro-4-quinolyl)-anthranilic acid," glyceryl esters are claimed as less irritating. Alternatively ulcerogenicity of indomethacin derivatives... 

R)-m-[(E)-2- 7-Chloro-2-quinolyl)vinyl]-a-[o-(1-hydtoxy-1-methylethyl)phenethyl]benzyl]thio]methyl]-cyclopropane acetic acid. Montelukast. Selective leukotriene 04 receptor antagonist. Used as an antiasthmatic. Merck Co.Inc. 

Ring closure of A-(2-pyridyl)- and A-(2-quinolyl)malonamates gave 2-chloro or 2-hydroxy-4-oxo-4/7-derivatives of (12) and its 6,7-benzologues <70HCA905, 81CCC2428,84S152,95EJM27). 

Chloro-4-quinolyl) amino]-a-(diethylamino)-o-cresol dihydrochloride dihydrate Phenol, 4-[(7-Chloro-4-quinolyl)-amino]-2-[(diethylamino) methyl]-dihydrochloride, dihydrate, Amodiachin Hydroehloride BP USP Int. P Ind. P ... 

Chloro-4-quinolyl] amino] pentyl] ethylamino] ethanol sulphate (1 1) (salt) Ethanol, 2-[[4-(7-chloro-4-quinolyl) amino]-pentyl] ethylamino]-, sulphate (1 1) salt Oxichlorochin Sulphate Hydrochloroquine Sulphate BP Hydroxychloroquine Sulfate USP ... 

R = phenyl, fiityl, indolyl, pipetxinyl and 2-chloro-7-methyl-quinolyl... 

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