Chitosan degradable

Kim KW, Thomas RL, Lee C, Park HJ. Antimicrobial activity of native chitosan, degraded chitosan, and O-carboxymethylated chitosan. J Food Prot 2003 66 1495-1498. 

Isolation of a chitosan degrading fungus, Penicillium spinulosum, and chitosanase production by the isolate ... 

A chitosan degrading fungus was isolated from chitosan and then identified as Penicillium spinulosum by the International Mycologjcal Institute, England. The isolate was used for the production of chitosanase in a salts medium with either chitosan or Rhizopus cell walls as the sole carbon source. Chitosanase was produced under all the conditions tested, however better yields were obtained by using Rhizopus cell walls. 

A chitosan degrading fungus, Penicillium spinulosum was isolated from chitosan and maintained on YPG agar excluding peptone (11). 

Weight Losses of the Film Samples by Using Incubated Chitosan- Degradation Bacteria (Sphingobacterium multivorum)... 

Molecular weight (MW) Low-MW chitosan degrades at a faster rate by lysozyme compared to high-MW chitosan. For example, chitosan with a MW of 200 kD degrades up to 90% in 35 days, while chitosan with a MW of 450 kD degrades up to 62% in 35 days. 

Current investigation is conducted to estimate the potential of using injectable material based on chitosan and its derivatives as a scaffold material for diverse tissue-engineering applications including cartilage, bone, and skin. Residual amount of acetyl content influences the chitosan degradation and degradation... 

However, few researches have been reported on the mechanism of these non-specific enzymatic processes, and even then controversial views exist. On the one hand, Kittur et al.[33] first reported that a multiple functional pectinase isoform from Aspergillus niger co i A be responsible for chitosan degradation by pectinases,but on the other hand, some authors have purified hetero chitosanases or/and chitinases from several commercial proteases,which were charged with their chitosanolytic activity [51-53].Whereas,no reports have been focused on non-specific hydrolysis of cellulases and lipases before, although their utility were popular in chitosan hydrolysis[5,8,9,10,28-31,43] and several bifunctional cellulase-chitosanases have been reported to be secreted from bacteria [58,79,87]. 

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