Chemotherapy sickness induced

Ginger 20 27.48 million (7) Chemotherapy-induced nausea, morning sickness, postoperative nausea and vomiting, vertigo Motion sickness... 

Antihistaminics Moderate efficacy in motion sickness and chemotherapy-induced emesis ... 

Phenothiazines such as prochlorperazine, thiethylperazine, and chlorpromazine see Chapter 18) are among the most commonly used antinauseants and antiemetics. Their principal mechanism of action is dopamine receptor antagonism at the CTZ. Compared to metoclopramide or ondansetron see above), these drugs do not appear to be as uniformly effective in cancer chemotherapy-induced emesis. On the other hand, they also possess antihistaminic and anticholinergic activities, which are of value in other forms of nausea, such as motion sickness. 

The most commonly used muscarinic receptor antagonist is scopolamine (hyoscine), which usually is administered as the free base in the form of a transdermal patch (transdee(M-scop). Its principal utility is in the prevention and treatment of motion sickness, although it also has some activity in postoperative nausea and vomiting. In general, anticholinergic agents have no role in chemotherapy-induced nausea. 

Diphenhydramine, dimenhydrinate, cyclizine, meclizine, and promethazine are used as anti-motion sickness drugs. Diphenhydramine is also used for management of chemotherapy-induced vomiting. 

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