Chemosensors design principles

Owing to the unique process of ligand-sensitized lanthanide luminescence emission, the design principle of lanthanide complex-based chemosensors is distinct from that of organic chemosensors [28]. As shown in Figure 13.4, lanthanide-based luminescent chemosensors... 

Figure 13.4 Typical design principle of lanthanide complex-based chemosensors based on binding of an analyte (an) (a) directly influencing the Ln(III) luminescence, (b) influencing photophysical properties of the ligand, and (c) addition of a sensitizing analyte onto a poorly luminescent lanthanide-containing sensor [1]. (Reproduced from J.C.G. Bunzli and C. Piguet, Taking advantage of luminescent lanthanide ions, Chemical Society Reviews, 34, 1048-1077, 2005, by permission of The Royal Society of Chemistry.)...

Synthetic chemosensors incorporate a synthetically manufactured element for recognition. While biomimetic receptors have been prepared, with synthetic receptors mimicking the active sites of naturally occurring biological molecules, synthetic receptors can be designed entirely from first principles. 

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