Chemoenzymic synthesis

Thiem,J. and Sauerbrei, B. (1991) Chemoenzymic synthesis of sialylohgosaccharides with immobilized sialidase. Angevr. Chem. Int. Ed. Engl., 30, 1521-1523. 

Thiem, J, Wiemann, T, Combined chemoenzymic synthesis of Al-glycoprotein synthons, Angew. Chem., 102, 78-80, 1990. 

Chemoenzymic synthesis of giycopeptide iibrary by Nishimura and co-workers... 

Li S-M (2009) Prenylated indole derivatives from fungi structure diversity, biological activities, biosynthesis and chemoenzymic synthesis. Nat Prod Rep 27 57-78... 

A comprehensive review (260 refs.) on the synthesis of carbohydrates from noncarbohydrate sources covers the use of benzene-derived diols and products of Sharpless asymmetric oxidation as starting materials, Dodoni s thiazole and Vogel s naked sugar approaches, as well as the application of enzyme-catalysed aldol condensations. The preparation of monosaccharides by enzyme-catalysed aldol condensations is also discussed in a review on recent advances in the chemoenzymic synthesis of carbohydrates and carbohydrate mimetics, in parts of reviews on the formation of carbon-carbon bonds by enzymic asymmetric synthesis and on carbohydrate-mediated biochemical recognition processes as potential targets for drug development, as well as in connection with the introduction of three Aldol Reaction Kits that provide dihydroxyacetone phosphate-dependent aldolases (27 refs.). A further review deals with the synthesis of carbohydrates by application of the nitrile oxide 1,3-dipolar cycloaddition (13 refs.). ... 

A review on the chemoenzymic synthesis of carbohydrates and carbohydrate mimetics features the use of aldolases in the synthesis of neuraminic acid and KDO analogues. ... 

The chemoenzymic synthesis of trimeric SiaLe decasaccharide 49 was achieved by enzymically sialylating and fucosylating the linear hexamer. The analogue... 

A number of reviews on the chemical synthesis of fluorinated carbohydrates have been published, as well as others covering the chemoenzymic synthesis of fluorosugars, the preparation and reactions of glycosyl fluorides, and the preparation of F-deo3 uorohexoses7... 

H.l.M. Gijsen, L. Qiao, W. Fitz, C.-H. Wong, Recent advances in the chemoenzymic synthesis of carbohydrates and carbohydrate mimetics, Chem. Rev. 96 (1996) 443-473. 

Kong, D. C. M. and Von Itzstein, M., The chemoenzymic synthesis of 9-substituted 3,9-dideoxy-D-glycero-D-galacto-2-nonulosonic acids. Carbohydr. Res. 1998, 305 (3-4), 323-329. 

Lebreton, (., Alphand, V., and Furstoss, R. (1996) A short chemoenzymic synthesis of (+)-multifidene and (+)-viridiene. Tetrahedron Lett., 37,1011-1014. 

Ohtani, T, Kikuchi, K, Kamezawa, M., Hamatani, H., Tachibana, H., Totani, T, and Naoshima, Y. (1996) Chemoenzymic synthesis of (+)-(4E,15F)-docosa-4,15-dien-l-yn-3-ol, a component of the marine sponge Crihrochalina vasculum. J. Chem. Soc. Perkin Trans. /, 961-962. 

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