Chemical copolymers Amino resins

The polyester resin used in this study, MR 13006 (Aristech Corporation), was supplied as a 60-wt% solution in styrene monomer. The epoxy resin, a digly-cidyl ether of bisphenol A (Epon 828), was obtained from Shell Chemical Company. The reactive liquid rubber, an amino-terminated butadiene-acrylonitrile copolymer (ATBN 1300 x 16), was provided by the BFGoodrich Company. The resin was mixed with additional styrene monomer to maintain the ratio of reactive unsaturation in the polyester-to-styrene monomer at 1 to 3. We added 1.5 wt% of tert-butylperbenzoate initiator to the solution, which we then degassed under vacuum. The mixture was poured between vertical, Teflon-coated, aluminum plates and cured under atmospheric pressure at 100 °C. In the modified compositions, the rubber was first dissolved in the styrene monomer, and then all the other components were added and the solution cured as described. In all the compositions, the ratio of the amine functions with respect to the epoxy functions was kept at 1 to ensure complete cure of the epoxy. 

Polystyrene resin, frequently used resin material for solid-phase peptide synthesis (SPPS). The polymeric support for SPPS must be chemically inert, mechanically stable, completely insoluble in the solvents used, and easily separated by filtration. For many applications a copolymer of polystyrene with 1% of divinyl benzene as crosslinker is used. The dry resin beads are able to swell up to the five-or sixfold volume in the different organic solvents mainly used for peptide synthesis (e.g., dichloromethane or dimethylfor-mamide). For SPPS the resin material must be chemically functionalized in order to allow for attachment of a handle/liker (e.g. Wang resin), or the first amino acid (—> Merrifield resin). Hydrophilic tentacle polymers gels (TentaGel) are obtained by grafting polyethylene glycol (PEG) chains with an arbitrary degree of polymerization onto porous polystyrene beads. 

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