Registry System, Chemical Abstracts Service

The 8(b) inventory accumulation was the next major activity. For a decentralized company like Monsanto or, for that matter, most major chemical companies, the experience of centralized information gathering was a new experience. However, we believe that the experience not only was novel, but proved to be beneficial from several points of view. First of all, it enabled us to evolve a network of expertise. Second it gave us a central data-base on which to build other information important from a corporate point of view, and permit a one-time expense for developing a system. Third, it revealed that we needed to improve our data files in some areas. And, fourth, it gave our central staff departments some surprises as to substance locations. We used the Chemical Abstract Service Registry Profile capabilities to gather all the known synonyms and added our internal numeric and common identifiers to access the file via dozens of possible names or numbers. 

All test and reference items should be identified with a Chemical Abstracts Service registry number or other unique code. Where test items are novel compounds supplied by the sponsor of the study, there should be an agreed-upon identification system to allow the item to be tracked through the study. The composition and concentrations of prepared solutions should be known and recorded. A sample for analytical purposes of each batch of test item should be retained for all except short-term studies. This requirement has the potential to overload storage facilities very quickly, and some sensible arrangement must be made to archive samples of importance, while not giving an inspector cause to worry about inappropriate disposal of items. 

Chemical Abstracts Service Registry Number (CASi) is a numeric designation assigned by the American Chemical Society s Chemical Abstracts Service and uniquely identifies a specific chemical compound. This entry allows one to conclusively identify a material regardless of the name or naming system used. 

Registry Number, which is unique to each compound, is used to link the structure with names, references, and other information within the Chemical Abstracts Service Registry Number System. However, there is no way to generate a Registry Number from a given structure, and data on specific compounds can only be recovered by finding the Registry Number first. The first formula index to use these numbers will be that for vol. 71 (1969). 

Storage of Polymer Structures. CAS has developed comprehensive sets of nomenclature rules and structure conventions that have become standards in the world of chemical literature (see Chemical Abstracts Service Information System). CAS selects polymers for indexing according to a set of rules (5). The Registry File records are created from chemical information published in books, patents, dissertations, scientific journal articles, etc. 

Each compound is characterized by its chemical name, net formula and Chemical Abstracts Service Registry Number (in square brackets). The data are ordered by the compound net formula in accordance to the Hill Indexing System [00-hil] (in each formula, carbon atoms are placed first, hydrogen atoms second, and further elements based on an alphabetical sequence). 

Graf, W. Kaindl, H.K. Kniess, H. I hmidt, B. Warszawski, R. Retrieval by Means of the BASIC Fragment Search Dictionary Bas on the Chemical Abstracts Service Registry III System . J. Chem. Inf. Comput. Sci. 1979,19, 51-55. 

A prominent example of a structure database (see Structure Databases) is the REGISTRY File offered by the host STN. This database contains both structure and nomenclature from the Registry System. This file is searched using the Messenger software developed by Chemical Abstracts Service, which provides both identity, full structure, and substructure searching as well as nomenclature searching (see Chemical Abstracts Service Information System). Structure queries are entered as structure diagrams created with text... 

The WLN was applied to indexing the Chemical Structure Index (CSI) at the Institute for Scientific Information (ISI) [13] and the Ituiex Chemicus Registry System (ICRS) as well as the Crossbow System of Imperial Chemical Industries (ICl). With the introduction of connection tables in the Chemical Abstracts Service (CAS) in 1965 and the advent of molecular editors in the 1970s, which directly produced connection tables, the WLN lost its importance. 

CA Search Data-Star, DIALOG, ORBIT, Questel, etc Chemical Abstracts Service international, chemistry limited bibhographic data deep indexing of chemical concepts compound registry searchable by stmcture on Questel and by name and molecular features on other systems... 

CAS = Chemical Abstracts Services DOT/UN/NA/IMCO = Department of Transportation/United Nations/North America/International Maritime Dangerous Goods Code EPA = Environmental Protection Agency HSDB = Hazardous Substance Data Bank NCI = National Cancer Institute NIOSH = National Institute for Occupational Safety and Health OHM/TADS = Oil and Hazardous Materials/Technical Assistance Data System RTECS = Registry of Toxic Effects of Chemical Substances... 

Weisgerber DW. Chemical Abstracts Service Chemical Registry System history, scope, and impacts. J Am Soc Inf Sci 1997 48 349-60. 

CAS registry number An identifying numberi ng system for chemicals called the Chemical Abstract Service (CAS) with individual numbers assigned by the American Chemical Society. CAS numbers identify specific chemicals and are assigned sequentially. Such a number is a concise and unique means of material identification. 

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