Ceramides from plasma

Preti A, Miyagi T, Sonnino S. Plasma membrane production of 53. ceramide from ganglioside GM3 in human fibroblasts. EASEB J. 2006 20 1227-1229. 

GC-MS has proved an efficient method for exploring the complex mixture of sphingomylins in human plasma [293]. They are first hydrolysed to ceramides, fractionated on TLC as their diacetates, converted to 1,3-di-O-trimethylsilyl ethers, and then identified. Ceramides from sphingomyelin fractions of beef brain and human plasma [283] have also... 

Navas, P, Femandez-Ayala, DM, Martin, SF, Lopez-Lluch, G, De Caboa, R, Rodriguez-Aguilera, JC and VUlalba, JM (2002) Ceramide-dependent caspase 3 activation is prevented by coenzyme Q from plasma membrane in serum-deprived cells. Free Radic... 

MDRl is a member of a family of ATP-dependent drug efflux pumps (32). Several of these pumps, including MDRl, have been shown to mediate lipid translocation and phospholipid bilayers (33). This translocation activity has been implicated in part as the mechanism for dmg efflux by which the hydrophobic cytotoxic drug is translocated from the cytosolic to the external leaflet of the plasma membrane bilayer. MDRl first was shown to translocate glucosyl ceramide analogs from the cytosolic to the external leaflet of the plasma membrane (33). However, the major glucosyl ceramide translocation activity of MDRl later... 

In a later paper it was established that ceramide 1-phosphate was released from the GIPLs by the PLD from rat blood plasma.17... 

---