Cellulose acetate butyrate microcapsules

Sayed HA, Price JC. Tablet properties and dissolution characteristics of compressed cellulose acetate butyrate microcapsules containing succinyl sulfathiazole. Drug Development and Industrial Pharmacy. 1986 12 577-587. 

Fundueanu, G., Constantin, M., Esposito, E., Cortesi, R., Nastruzzi, C., and Menegatti, E. (2005). Cellulose acetate butyrate microcapsules containing dextran ion-exchange resins as self-propelled drug release system, Binmaterials. 26,4337-4347. 

Precise dosage of reactive components is essential for the reproducible hardening of dental cements, without adversely affecting the physical properties of the hardened product. Cellulose acetate butyrate microcapsules containing poly(acrylic acid) prepared by phase separahon when mixed with glass ionomer powder result in single-phase, free-flowing powders [64]. The contents of microcapsules can be released and become mixed with the solid phase by mechanical stress, vibration microwaves, and/or sonicahon. 

Polyamide, collodion (cellulose nitrate), ethylcellulose, cellulose acetate butyrate or silicone polymers have been used for preparation of permanent microcapsules. This method offers a double specificity due to the presence of both the enzyme and a semipermeable membrane. Moreover, it allows simultaneous immobilization of many enzymes in a single step and the surface area for contacting the substrate and the catalyst is large. The need of high protein concentration and the restriction to low molecular weight substrates are the main limitations of enzyme microencapsulation. 

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