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Cellular toxicology assays

Lee MY, Kumar RA, Sukumaran SM, Hogg MG, Clark DS, Dordick IS. Three-dimensional cellular microarray for high-throughput toxicology assays. Proc. Natl. Acad. Sci. U.S.A. 2008 105 59-63. [Pg.705]

Peters, M.F., Lamore, S.D., Guo, L., Scott, C.W., Kolaja, K.L. (2015). Human stem cell-derived cardiomyocytes in cellular impedance assays bringing cardiotoxicity screening to the front hue. Cardiovascular Toxicology, 15, 127—139. [Pg.25]

In the following chapter, we introduce HCI assay methods which can be used to identify cytotoxicity, other drug-induced specific toxicologically relevant events, as well as assays for the assessment of cellular morphology and functions. An overview of cellular features associated with potential toxic effects for which specific assays can be applied are shown in Fig. 1. Microscopy images selected from assays are shown in Fig. 2. [Pg.380]

Scott, C.W., Zhang, X., Abi-Gerges, N., Lamore, S.D., Abassi, Y.A., Peters, M.R (2014). An impedance-based cellular assay using human iPSC-derived cardiomyocytes to quantify modulators of cardiac contractility. Toxicological Sciences, 142, 331-338. [Pg.26]


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See also in sourсe #XX -- [ Pg.2 , Pg.76 ]

See also in sourсe #XX -- [ Pg.76 ]




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