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Cellular high-content screening

Smaller compound sets and focused compound libraries can be used to screen more broadly for physiological phenotypes. In the typical high-content screening experiment, the effects of compounds on cellular assays are captured... [Pg.6]

Baatz, M. et al. 2006. Object-oriented image analysis for high content screening detailed quantification of cells and sub cellular structures with the Cellenger software. Cytometry A 69, 652-658. [Pg.154]

High-content screen (HCS) is a phenotypic screening that monitors multiple cellular parameters simultaneously. HCS employs fluorescence-based reagents (antibodies, dyes that bind or localize to a given cell component, sensors) to generate a multicolor fluorescence readout that is usually recorded using automated optical image acquisition devices. [Pg.239]

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See also in sourсe #XX -- [ Pg.550 ]



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