Cell survival pathways primordial

The RNA/DNA-transformed cells regained the extraordinary vitality of ancient primordial unicellular organisms and readily mobilize all possible cell survival pathways . On occasions, the cancer cell fuses with a mesenchymal cell (the tumor-supportive subverted fibroblast or macrophage). These cell fusions were recently discussed in a Springer publication of authors/editors Dittmar Zanker [1541]. This author proposed that endogenous retroviruses that frequendy appear budding from maUgnandy transformed lymphoma, melanoma and adenocarcinoma cells, mediate these cell fusions [26, 27]. 

Comment. It was a response to physico-chemical inducers,that the ancient cells managed to survive by activating their cell survival pathways. Antiviral self-defense mechanisms were installed. In the end, the descendants of the single cells, and their viruses both remain in existence, forming the largest biomass on Earth. The primordial cell survival pathways remained conserved in the form of much more elaborate, and interrelated sequences In the stem and somatic cells of multicellular hosts. In addition to physico-chemical inducers, it is an armada of biological agents... 

In Self-defense, the Cancer Cell Reactivates Its Primordial Genome Loaded with Proviruses in Order to Activate All Its Remaining Survival Pathways... 

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