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Cell culture, murine tumor systems including

Mammalian cell suspension cultures are the preferred choice for large-scale recombinant protein production in stirred-tank bioreactors. The most widely used systems are Chinese hamster ovary (CHO) cells and the murine myeloma fines NSO and SP2/0. In half of the biological license approvals from 1996-2000, CHO cells were used for the production of monoclonal antibodies and other recombinant glycosylated proteins, including tPA (tissue plasminogen activator) and an IgGl fusion with the tumor necrosis factor (TNF) receptor, the latter marketed as Enbrel [7]. [Pg.267]

See other pages where Cell culture, murine tumor systems including is mentioned: [Pg.30]    [Pg.461]    [Pg.460]    [Pg.18]    [Pg.3881]    [Pg.545]    [Pg.257]    [Pg.66]   


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Cell culture systems

Cultural system

Murine

Murine cells

Murine tumors

Tumor cell cultures

Tumor cells

Tumoral cells

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