Cavity inclusions

Fig. 1. Schematic representation of a receptor—substrate (host—guest) complex involving cavity inclusion of the substrate and the formation of different types of weak supramolecular interactions between receptor (hatched) and substrate (dotted).

Extramolecular Cavity Inclusions Lattice-Type Inclusion Compounds, Clathrates... 

Isaacs N, Nichols P, Raston C et al. (1997) Solution volume studies of a deep cavity inclusion complex of C p-benzyl calyx[5]arene. Chem Commun. 19 1839-1840. 

Chemical Sensing Based on Cavity Inclusion Sensing Based on Interactions with Nonpolar Moieties of Guests... 

Figure 7.29 X-ray crystal structure of the l,2-dicarbadodecaborane(12) cavity inclusion complex with CTV.36...

In LC, cyclodextrins have been used in both the mobile and stationary phases, although the latter application predominates using bonded phases. Both normal and reversed phase separations are possible. With polar mobile phases, the cyclodextrin cavity hosts and retains hydrophobic analytes but when large concentrations of organic solvent are used in the mobile phase, solvent molecules occupy the cavity—inclusion of analytes is suppressed and hydrogen bonding and dipole-dipole interactions with analytes predominate. Applications to electrochromatography have also been described. [96]... 

Farthing also reported the synthesis of compound 6.8 Advancements in cyclophane receptor chemistry came in 1955, when Stetter and Roos recognized the ability of cyclophanes to form inclusion complexes. They reported what they thought to be cavity inclusion complexation of benzene in cyclophane 7.9 This opened the door to the study of inclusion complexation with cyclophanes. However, in the early 1980 s when the crystal structure of Stetter s complex was solved it was shown that the benzene was located between two host molecules and not inside the... 

The main defects revealed have been cracks and micro-cracks cavity inclusions, due to the welding process or to the quality of the adopted gas discontinuity of the weld bead weld sticking segregation lines of inter-metallic and not-metallic (silicates, oxides, etc.) compounds, in the thickness centre of welded plates, imputable to the materials quality. 

G. Pistolis, E. Hadjoudis, and I. M. Mavridis, Photoactivity with cyclodextrin cavities Inclusion complexes of anils with cyclodextrins Mol. Cryst. Liq. Cryst. Sci. Technol., Sect. A 242,483-487 (1994). 

Holman, K.T. Atwood, J.L. Steed. J.W. Intra cavity inclusion of [CpFe Varene)] guests by cyclotriveratrylene. Angew. Chem., Int. Ed. Engl. 1997. 36. 1736-1738. 

The number of papers reporting the role of CH/ti interaction is rapidly increasing. Only recent key papers are cited here. Chloroform interacts favorably with an arene n-oloud of fullerene complexes of calixarenes " and cyclotriveratrylene. Evidence for the role of CH/ti interaction in self-assembly was presented.The significance in molecular capsules " " and lattice- and cavity-inclusion type clathrates is well documented. 

It has been successfully demonstrated by the authors that macro cyclic heterocyclophanes 1-3 exhibit enzyme-like or rdceptor-like functions with remarkable substrate specificity in the solution phase Heterocyclophane 1 is of considerable interest, since 1 forms a molecular cavity inclusion crystal which is to be differentiated from the lattice (cavity) inclusion and an interesting guest-dependent polymorphism and plane chirality in the crystalline phase have been observed K... 

The typical examples of macrocyclic cyclophanes, e.g., cyclotriver-atrylene, cyclotricatechylene, or tri-O-thymotide, form clathrate compounds. Significant host-host interaction affords a cage or a channel between the host molecules for guest accomodation in these lattice (cavity) inclusion crystals, (Host) (Guest). ... 

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