Cation self-regenerating suppressor

Modem suppressors for cation chromatography are both efficient and self-regenerating. The principles are similar to the suppressors for anion chromatography, described in Chapter 6. The mechanism of suppression for a cation self-regenerating suppressor is illustrated in Fig. 7.1 and described in some detail by Rabin et al. [3]. Suppressors for cation chromatography are limited to those cations that do not form precipitates with the hydroxide ions from the suppressor. 

Figure 7.1. Mechanism of suppression for the cation self-regenerating suppressor. fT MSA = Methane-sulfonic acid. From Ret [3] with permission.

Self-regenerating suppressor cartridge incorporating an electrolysis cell, (a) For anionic analytes, (b) For cationic analytes. 

The schematics and operation of the CSRS self-regenerating suppressor suitable for cation-exchange chromatography corresponds to the ASRS, which was developed for anion-exchange chromatography (see Section 3.6.4). Both suppressor systems were introduced in 1992 [25,26]. Since then, dynamic suppression capacity has been improved they have developed into the SRS 300 type suppressors now being available on the market The principle schematic of a CSRS only... 

This benchmark publication was followed by a series of developments that continues to this day in the evolution of IC as a trace determinative technique. The Dionex Corporation was formed out of these developments from Dow Chemical in the mid-1970s and this company has been quite an innovator in the manufacture of instrumentation for suppressed IC. From the earlier model such as the 10 to the 20001 to the DX 500 from the cation-exchange column to the hollow-fiber cation suppressor to the micro-membrane cation suppressor to the self-regenerate cation suppression for anion analysis and now to their just add water slogan, Dionex Corporation has made considerable advances in IC technology. A nonsuppressed form of IC also developed during the 1970s. To quote from the author s abstract of this benchmark paper (97) ... 

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