Catha

Ephedrine also oeeurs in the leaves of the yew tree [Taxus baccata) and in Sida rhombifolia Linn, whilst Stockman s cathine from Catha edulis Forsk has been shown by Wolfes to be d-nor- -ephedrine. Ghosh, Chopra and Dutt state that the bark of Moringa pterygosperma Gaertn. contains two alkaloids similar to ephedrine in pharmacological action. The more active of the two, moringinine, is amorphous the other is a liquid but jdelds a crystalline hydrochloride, C,H. HCl, m.p. 254-4°, + 1-8°, a picrate, m.p. 195°, and an aurichloride, m.p. 170-8°. [Pg.635]

Patel NB. Mechanism of action of cathinone the active ingredient of khat (Catha... [Pg.163]

Cathinone An amphetamine derivative found in khat extracted from Catha edulis growing in the Horn of Africa, where it is widely used as a recreational stimulant. [Pg.239]

Khat (Qat) The Horn of Africa plant Catha edulis containing the amphetamine-like drugs, cathine and cathinone (norpseudoephedrine). [Pg.244]

Guantai AN, Mwangi JW, Muriuki G, Kuria KA. (1987). Effects of the active constituents of Catha edulis on the neuromuscular junction. Neuropharmacology. 26(5) 401-5. [Pg.453]

Halket JM, Karasu Z, Murray-Lyon IM. (1995). Plasma cathinone levels following chewing khat leaves (Catha edulis Forsk.). J Ethnopharmacol. 49(2) 111-13. [Pg.453]

Kalix P. (1991). The pharmacology of psychoactive alkaloids from ephedra and catha. J Ethnopharmacol. 32(1-3) 201-8. [Pg.454]

Nencini P, Amiconi G, Befani 0, Abdullahi MA, Anania MC. (1984). Possible involvement of amine oxidase inhibition in the sympathetic activation induced by khat (Catha edulis) chewing in humans. J Ethnopharmacol. 11 179-86. [Pg.458]

Taha SA, Ageel AM, Islam MW, GInawl OT. (1995). Effect of (-)-cathinone, a psychoactive alkaloid from khat (Catha edulis Forsk.) and caffeine on sexual behaviour in rats. Pharmacol Res. 31(5) 299-303. [Pg.465]

Yu G, Maskray V, Jackson SH, Swift CG, Tiplady B. (1991). A comparison of the central nervous system effects of caffeine and theophylline in elderly subjects. BrJ Clin Pharmacol. 32(3) 341-45. Zelger JL, Carlini EA. (1980). Anorexigenic effects of two amines obtained from Catha edulis Forsk. (Khat) in rats. Pharmacol Biochem Behav. 12(5) 701-5. [Pg.468]

Khat Catha edulis Leaves Alkaloids cathinone, cathine Chewed, tea Stimulant Yemenis, Ethiopians, Somalis etc. East Arabia, East Africa, Madagascar... [Pg.292]

Chiral protoalkaloids, such as cathinone (55), a psychotropic constituent of Catha edulis Forssk. (khat), have provided probes for studying the mechanistic properties of biogenic amine transporters, and afforded information regarding the effect of stereochemistry at the transportation level of these nitrogenous compounds. ... [Pg.30]

Ecstasy synthesis patterned on cathinone from Catha edulis Forsk., Celestraceae, Ang. [Pg.199]

Khat Catha edulis Ephedrine, cathinone Adrenergic Norepinephrine, epinephrine... [Pg.180]

Al-Hebshi NN Skaug N (2005). Khat (Catha edulis) - an updated review. Addiction Biology, 10, 299-307... [Pg.149]

A constituent of Ephedra smica A constituent of Catha edulis Colloquially known as Speed... [Pg.297]

Some examples of the use of nitrogen nucleophiles as the key step in organic syntheses include the preparation of pyrroles (equation 58),201-202 a number of alkaloids203 207 includi ibogamine, catha-ranthine205-206 and perhydrohistrionicotoxin,207 amino sugars (equation 59), 5-amino-l,3-penta-dienes209 and 1-azaspirocycles.210... [Pg.598]

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