Catalytic Iron-mediated Synthesis through -H Activation Strategies

1 Catalytic Iron-mediated Synthesis through C-H Activation Strategies 

Cross-coupling via C-H activation Cross Dehydrogenative Coupling 

Iron-catalysed direct Suzuki-Miyaura cross-coupling between Af-het-erocyclic amines and aryl boronic acids. 

In spite of the impressive advancements and improved catalytic potential in the area of iron-catalysed carbon-hydrogen activation, it still remains a challenging research topic. An impressive number of efficient, selective and, in some cases, remarkably sustainable iron-catalysed carbon-hydrogen activation processes have been developed in recent years, nevertheless it is clear that further studies are required to elucidate the nature of these transformations and to develop the next generation of iron catalysts. Although some key mechanistic steps have been elucidated, the likely coexistence of mixed-valence iron species complicates the mechanistic studies. On the other hand, the reported number of diverse and synthetically relevant iron-catalysed carbon-hydrogen activation procedures underline the 

2 Other Cross-coupling Chemistry Using Iron-based Catalysts 

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