Case-study PBLx exposure from fish ingestion

3 Case-study PBLx exposure from fish ingestion 

As a specific case-study, we constructed information on a chemical designated as PBLx. This compound is persistent both in the ambient environment and in human tissues. It is also 

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For any case-study built around Equation 1, we have to consider, for model input, parameters that provide emissions or environmental concentrations, intermedia transfer factors, ingestion (or other intake) rates, body weight, exposure frequency and exposure duration. For our specific case-study below, we are interested in concentrations in surface waters due to deposition from the atmosphere. The relevant intermedia transfer factor is the bioconcentration factor for fish concentration from surface water concentrations. The intake data we need are the magnitude and range of fish ingestion in our exposed population. Because PBLx is a persistent compound that accumulates in fat tissues, we will focus for this case not on exposure frequency and duration but on long-term average daily consumption. 

In this case-study, the issue of concern is the extensive exposure of human populations to PBLx, which is a persistent pollutant with multimedia and multipathway exposure potential. For PBLx, exposures occur primarily through food pathways. Here we focus on fish ingestion exposures from PBLx emissions to air that are deposited on ocean and fresh waters and accumulated in both ocean and freshwater fish. This situation focuses attention on three key pieces of information—concentration in water, biotransfer to fish and human consumption of fish. 

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