Cascadane

Cascadanes consist exclusively of molecules of the same kind and the same weight with correct, regularly branched, or perfect, defect-free structure [40]. 

If parts of dendrimers and cascadanes acts as substituents or functional groups of molecules, then they are called dendrons, or - if defect-free - casca-dons. 

If cascadanes form host/guest complexes, for example by inclusion of smaller guest molecules, then they are designated as cascadaplexes, corresponding den-drimer-based complexes are known as dendriplexes (Fig. 1.20) [40]. 

In the case of complex dendrimers with differing branches or differing dendryl substituents on a non-dendritic scaffold it is necessary to include further details in the name. For this reason, a more detailed cascadane nomenclature [45] has been developed, according to which the above POPAM would be called ... 

Rule 3 If a molecule contains one dendritic structure part or only different ones, the dendritic structures (=dendrons) are treated as substituents and are assigned the suffix -cascadyl. If at least two dendrons in a molecule are of the same kind, then the name is given the suffix -cascadane (Fig. 1.22). 

Further examples of cascadane nomenclature are given below for the sake of illustration. The reader is referred to the original literature for further explanations and rules [45]. 

According to cascadane nomenclature, the second-generation PAMAM dendri-mer shown in Fig. 1.25 has the name ... 

Attempts will be made to gain access to accurate purity or defect information for individual dendrimers, which will permit uniform classification of a substance as a pure cascadane or hyperbranched compound with a higher or lower degree of dispersion. 

Friedhofen and Vogtle have recently outlined a detailed nomenclature for dendrimers which is discussed in the Section Key Reference. In brief, a dendrimer is defined as comprising a series of self-resembling units, termed dendrons, linked by a common core. The dendrons are referred to as cascadyl-substituents or, if there is more than one identical dendron, the molecule is termed a cascadane. 

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