Cascadane nomenclature

In the case of complex dendrimers with differing branches or differing dendryl substituents on a non-dendritic scaffold it is necessary to include further details in the name. For this reason, a more detailed cascadane nomenclature [45] has been developed, according to which the above POPAM would be called  

As a consequence of the complex molecular structures, such nomenclatures are not without complications and require numerous rules. However - unlike the IUPAC [46] or nodal nomenclature [47] - owing to their modular structure they quickly reveal important individual characteristics (number of generations, number of terminal groups), which is of benefit in the laboratory and also in computer searches. 

The individual rules are reduced here to their bare essentials more detailed information will be found in the original literature [45]. 

Rule 1 Dendritic structures consist of self-similar units (fractals). 

Rule 2 A dendritic structure consists of a core unit and a dendritic unit 

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Further examples of cascadane nomenclature are given below for the sake of illustration. The reader is referred to the original literature for further explanations and rules [45]. 

According to cascadane nomenclature, the second-generation PAMAM dendri-mer shown in Fig. 1.25 has the name ... 

Friedhofen and Vogtle have recently outlined a detailed nomenclature for dendrimers which is discussed in the Section Key Reference. In brief, a dendrimer is defined as comprising a series of self-resembling units, termed dendrons, linked by a common core. The dendrons are referred to as cascadyl-substituents or, if there is more than one identical dendron, the molecule is termed a cascadane. 

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