Photosensitization, cardiovascular system

Quercetin and rutin suppressed photosensitized hemolysis of human erythrocytes with ho values equal to 40 p.mol l-1 and 150 jjlmt>I I 1, respectively [139]. Suppression of photohemolysis was accompanied by inhibition of lipid peroxidation. Morin inhibited oxygen radical-mediated damage induced by superoxide or peroxyl radicals to the human cells in the cardiovascular system, erythrocytes, ventricular myocytes, and saphenous vein endothelial cells [140]. Rutin protected against hemoglobin oxidation inside erythrocytes stimulated by prooxidant primaquine [141],... 

Like the examples cited above, there are several current hot topics of research in photosensitization, including the use of photodynamic therapy for malignancies, the use of photosensitizers as model systems for studying physiological and pathological processes involving reactive oxygen species, the development of model systems to produce cerebral ischemia, the use as antimicrobials and to treat blood and blood products, and photosensitization in the cardiovascular system, the main topic area of this review. 

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