Cardiovascular repair

It is now obvious that cell-based repair is feasible—both early and later in the CVD continuum. In fact, cell therapy may offer an unparalleled opportunity for cardiac and vascular functional improvement to millions living with CVD. Yet, many questions about the technology remain unanswered. Whether the best cell type, delivery method, or route of administration exists is unclear. The mechanisms associated with cardiovascular repair remain unknown, and, whether cell-based disease prevention is feasible is still unanswerable. 

A.F. Godier-Furnemont, T.R Martens, M.S. Koeckert, L. Wan, J. Parks, K. Aral, et al., Composite scaffold provides a cell delivery platform for cardiovascular repair, Proc. Natl. Acad. Sci. U.S.A. 108 (2011)7974-7979. 

Park J, Huang N, Kurpinski K, Patel S, Hsu S and Li S (2007). Mechanobiology of mesenchymal stem cells and their use in cardiovascular repair . Front. Biosci., 12,5098-5116. 

Psaltis, P. J., Zannettino, A. C., Worthley, S. G., and Gronthos, S. 2008. Concise review Mesenchymal stromal cells Potential for cardiovascular repair. Stem Cells, 26,2201-10. 

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