2-Carboxyethyl acrylate

CTMA Acrylamide/JV,J T -methylenebisacryl-amide, carboxyethyl acrylate, acrylic acid, Hexagonal No phase transition Macroporous layer-like morphology Phase separation between template and polymer [52]... 

Kim MS, Choi YJ et al (2007) Synthesis and characterization of in situ chitosan-based hydrogel via grafting of carboxyethyl acrylate. J Biomed Mater Res A 83A 674—682... 

Propenoic acid, 2-carboxyethyl ester. See 3-Carboxyethyl acrylate 2-Propenoic acid, 2-(diethylamino)ethyl ester. See DIethylaminoethyl acrylate... 

Zoco 624 Zoco 627 Zoco 672 Carboxyethyl acrylate, Casioroil,... 

Bis (triethoxysilyl) ethane Cl3-15 amine p-Carboxyethyl acrylate 4-Chlorophenol Copolyvidone... 

Carboxyethyl acrylate Cetoleth-13 Cetoleth-19 Cetoleth-20 Cl 1-15 pareth-15... 

Sodium P-carboxyethyl acrylate C H7NaOe Sodium ascorbate (C6H7NaOe)n Algin... 

Carboxyethyl acrylate Dimethyl fumarate Dimethyl maleate Ethyl fumarate (C6H8O4 C3H60)x PVM/MA copolymer, ethyl ester C6H806... 

In the presence of strong alkali dialkyl phosphites can be added to unsaturated compounds. Thus salts of carboxyethyl- or dicarboxyethylphosphonic acid are obtained by addition of dialkyl phosphites to methyl acrylate [99] in the presence of sodium methylate in methanol. Diethylmaleate similarly gave diethyldiethylphosphonosuccinate [100], according to Eqs. (55) and (56) ... 

Conjugation with sulfhydryl groups appears to be an important detoxification process for mctin l acrylate m the guinea-pig. The thioethers were identified as A -acct l-S -(2-carboxyethyl)-L-cysteine and the corresponding monomethyl ester, with a ratio between the two metabolites of 20 1. In male rats exposed to metliyl acrylate by inhalation, depletion of nonprotein sulfhydryl compounds was most pronounced in the lung, compared to liver, kidney and blood. After administration of methyl acrylate to Wistar rats, no hydroxymercapturic acid that might be derived from the epoxide of methyl acrylate was detected. It seems unlikely, therefore, that epoxidation of the acrylic esters occurs in vivo (lARC, 1986). 

A homolog of carboxymethylcellulose, the carboxyethyl derivative, can be prepared by the condensation of such acrylic derivatives as acrylamide with alkali-cellulose.30 The homolog is water-soluble, and gives a clear, viscous solution. Proposed uses are similar to those mentioned for the carboxymethyl ether. 

These materials are the reaction product of a primary amine and either acrylic acid, an ester of acrylic acid such as methyl acrylate, ethyl acrylate or crotonic acid. Either 1 or 2 mol of acrylate is used. If 1 mol is added, an N-alkyl (3-alanine is produced (Figure 6.6) and if 2 mol of acrylate per mole of amine is used, the corresponding carboxyethyl (3 -alanine derivative is produced (Figure 6.7). 

Carboxyethylation of enamines occurs on heating with / -propiolactone. A <5-keto-carboxylic acid amide is produced directly in high yield in the absence of water165 (Scheme 65). The same product was obtained on replacing / -propiolactone by acrylic acid, and saturated carboxylic acids gave cyclohexanone and the corresponding carboxylic acid amide. 

The reaction of glycidyl acrylate with a-(2-carboxyethyl)benzoin methyl ether has allowed one to obtain [101] the corresponding acrylic monomer which, upon copolymerization with different amounts of MMA, butyl methacrylate and 2-(V, V-dimethylamino)ethyl methacrylate, gives rise to polymeric photoinitiators, containing side-chain benzoin methylether moieties, for photocurable coatings ... 

V-carboxyethyl-substiluted macrocycles have been prepared by nucleophilic substitution using 2-bromopropionic acid, and by Michael addition of acrylic acid, acrylonitrile, or acrylamide, followed by hydrolysis. The formation constants with cations are lower than for carboxymethyl analogues and structures of lanthanide compounds are generally -carboxylato polymeric, often with the nitrogen atoms not coordinated. 

Phthalazine (51) and acrylic acid gave 3-(2-phthalazinio)propionate (52) [reactants, AcOEt (or CHCI3, Et20, etc.), reflux, 3h 81%, as an acrylic acid solvate] and thence 2-(2-carboxyethyl)phthalazinium chloride (53) (HCl, no... 

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