Amides carbons

Nearly all of the polymers produced by step-growth polymerization contain heteroatoms and/or aromatic rings in the backbone. One exception is polymers produced from acyclic diene metathesis (ADMET) polymerization.22 Hydrocarbon polymers with carbon-carbon double bonds are readily produced using ADMET polymerization techniques. Polyesters, polycarbonates, polyamides, and polyurethanes can be produced from aliphatic monomers with appropriate functional groups (Fig. 1.1). In these aliphatic polymers, the concentration of the linking groups (ester, carbonate, amide, or urethane) in the backbone greatly influences the physical properties. 

Amide-linked catenanes and rotaxanes, readily accessible via nonionic template synthesis, are molecules with fascinating topology, but their final breakthrough was only achieved when they became substrates for further chemical derivatiza-tion. A potential reaction site in the catenanes and rotaxanes presented so far is the sulfonamide group, because the proton can be selectively abstracted in the presence of carbon amide groups. Subsequent alkylation offers numerous possibilities of catenane and rotaxane chemistry. 

Benzamide Benzoyl amide Benzene Carbon Amide or Benzoic Acid Amidefcailed Benzamid or Benzol-saure-amid in Ger), CgH6.CO.NH2 mw 121.13,... 

The first comprehensive set of data on the oxidation reactions of nonaqueous electrolyte solutions, as well as their positive anodic limit for use in electrochemistry, was prepared by Mann [13]. Table 5 summarizes some useful selected data from his review. This data is representative for several families of organic solvents, including ethers, organic carbonates, amides, acids, and alcohols, in terms of anodic potential limits. 

Tables VIII and IX show that the position of the carbon-amide group is important. With both pairs of compounds, ours and the pair of Temin, higher glass temperatures of the polyamides are obtained if the carboxylic groups are attached to the ring. The products with the...

In the Cl symmetry strategy, the conformation of the carbonyl carbon-amide... 

Passive hydrolysis. Esters, carbonates, amides and urethanes are susceptible to hydrolysis. Drugs linked with the spacer via such bonds will be released in aqueous media. The rate of release will decrease in the order ester > carbonate > urethane > amide. Cleavage may also occur at the level of the spacer-backbone bond so that spacer-drug moieties can be released as well. 

I. Ugi and J. Geller The selective Cleavage of Carbon-amide Groupsy and the Synthesis of B-Lactam Antibiotics by Four Component Condensation Chem. Scripta 22 (1983) 85-89. 

STRATEGY AND ANSWER We begin by recognizing that 2-propanamine has a primary amine group bonded to a secondary carbon. Neither a three-carbon nitrile nor a three-carbon amide can lead to this structural unit from a C3 starting material. An oxime can lead to the proper structure, but we must start with a three-carbon ketone rather than an aldehyde. Therefore, we choose propanone as our starting material, convert it to an oxime, and then reduce the oxime to an amine. 

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