Capsules, drug carriers

Wilding, I. Prior, D.V. Remote controlled release capsules in human drug absorption (HDA) studies. Crit. Rev. Ther. Drug Carrier Syst. 2003, 20, 405-431. 

Stearic acid is widely used in oral and topical pbarmaceutical formulations. It is mainly used in oral formulations as a tablet and capsule lubricant see Table I, although it may also be used as a binder or in combination with shellac as a tablet coating. It has also been suggested that stearic acid may be used as a sustained-release drug carrier. ... 

Uses Dispersant, lubricant, anticaking agent, carrier, solvent, solubilizer, suspending agent for cosmetics, pharmaceuticals (oral, external, suppositories), dietetic prods. solvent for lipophilic drugs carrier, filler in capsules spreading agent, penetrant on skin... 

Uses Solubilizer for pharmaceutical drugs carrier ehicle for drugs in capsules ... 

The next two chapters concern nanostructured core particles. Chapter 13 provides examples of nano-fabrication of cored colloidal particles and hollow capsules. These systems and the synthetic methods used to prepare them are exceptionally adaptable for applications in physical and biological fields. Chapter 14, discusses reversed micelles from the theoretical viewpoint, as well as their use as nano-hosts for solvents and drugs and as carriers and reactors. 

The stability... under the conditions of administration will in most cases be the stability of the article/carrier mixtures determined under 58.113(a)(2). If a drug is administered as a powder (e.g., by capsule), the stabihty of the bulk drug determined under 58,105(b) will be reported. 

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