Cap ‘n’ collar

Ma Q, Kinneer K, Bi Y, Chan JY, Kan YW. Induction of murine NAD(P)H quinone oxidoreductase by 2,3,7,8-tetrachlorodibenzo-p-dioxin requires the CNC (cap n collar) basic leucine zipper transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) cross-interaction between AhR (aryl hydrocarbon receptor) and Nrf2 signal transduction. Biochem J 2004 377 205-213. 

CNC Cap n Collar family of basic leucine zipper proteins... 

Walker A Motif A motif described in SKN-1, a transcription factor in Caenorhabditis ele-gans. See Walker, A.K., See, R., Batchelder, C. et al., A conserved transcription motif suggesting functional parallels between Caenorhabitis ele-gans SKN-1 and Cap n Collar-related basic leucine zipper proteins, J. Biol. Chem. 275, 22166-22171, 2000. 

McMahon, M., Itoh, K. et al.. The Cap n Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes. Cancer Res., 61, 3299-3307, 2001. 

Alam J, Stewart D, Touchard C, Boina-pally S, Choi AMK, et al. 1999. Nrf2, a Cap n Collar transcription factor, regulates induction of the heme oxigenase-1 gene. J. Biol. Chem. 274 26071-78... 

Kobayashi A, Ito E, Toki T, Kogame K, Takahashi S, et al. 1999. Molecular cloning and functional characterization of a new cap n collar family transcription factor NrG.J. Biol. Chem. 274 6443-52... 

Veraksa, A., N. McGinnis, X. Li, J. Mohler and W. McGinnis. Cap n collar B cooperates with a small Maf subunit to specify pharyngeal development and suppress deformed homeotic function in the Drosophila head. Development 127 4023-4037, 2000. 

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