Candida dubliniensis

Sullivan DJ, Westerneng TJ, Haynes KA, Bennett DE, Coleman DC Candida dubliniensis sp. nov. Phenotypic and molecular characterization of a novel species associated with oral candidosis in HIV-infected individuals. Microbiology 1995 141 1507-1521. 

Pincus DH Rapid identification of Candida dubliniensis with commercial yeast identification systems. J Clin Microbiol 1999 37 3533-3539. 

Jabra-Rizk MA, Shirtliff ME, James C, Meiller TF (2006) Effect of famesol on fluconazole resistance in Candida dubliniensis. FEMS Yeast Res 6 1063... 

Disney, M. D. Stephenson, R. Wright, T. W. Haidaris, C. G. Turner, D. H. Gigliotti, F. Activity of Hoechst 33258 against Pneumocystis carinii f. sp. muris, Candida albicans, and Candida dubliniensis. Antimicrob. Agents Chemother. 2005, 49,1326-1330. 

Thibane, V.S., Kock, J.LF., Ells, R., van Wyk, P.W.J., and Pohl, C.H. (2010) Effect of marine polyunsaturated fiitty adds on biofilm formation of Candida albicans and Candida dubliniensis. Mar. Drugs, 8, 2597-2604. 

Until recently, a rapid presumptive identification of C. albicans could be made by incubation of the organism in serum formation of a germ tube (the beginning of hyphae, which arise as perpendicular extensions from the yeast cell, with no constriction at their point of origin) within 1 to 2 hours offered a positive identification of C. albicans. Unformnately, C. dubliniensis, a new species of Candida that was identified recently as an important cause of mucosal colonization and infection in HIV-infected individuals, also can produce a germ mbe. A negative germ tube test does not rule out the possibility of C. albicans, but further biochemical tests must be performed to differentiate between other non-albicans species. ... 

It has recently been shown that long-chain (n-3)-poly-unsaturated fatty adds such as 18 4n-3 (stearidonic acid), 20 5n-3 (ERA) and 22 5n-3 significantly inhibit the formation of Candida albicans and C. dubliniensis biofilms (Thibane et al., 2010). For a recent review on natural antifouling, see Qian, Xu, and Fusetani (2010). 

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