Candida albicans polysaccharide

Roesler, I. et al., Application of purified polysaccharides from cell cultures of the plant Echinacea purpurea to mice mediates protection against systemic infections with Listeria monocytogenes and Candida albicans, Int J Immunopharmacol, 13, 27, 1991. 

Steinmuller, C. et al., Polysaccharides isolated from plant cell cultures of Echinacea purpurea enhance the resistance of immunosuppressed mice against systemic infections with Candida albicans and Listeria monocytogenes, Int J Immunopharmacol, 15, 605, 1993. 

Most of the fungal cell wall is composed of polysaccharides (80-90%) with the remainder consisting mainly of lipid and protein. There seems to be no correlation between cell wall lipid amounts and the genus examined. Most of the cell wall lipid is bound and relatively difficult to extract. In S.cerevisiae, neutral lipids and phosphoglycerides are major components while in Candida albicans sterol esters, sterols, fatty acids, triacylglycerols and phospholipids are all contained. Thus, in contrast to Saccharomyces spp., the Candida spp. contain mainly sterols and sterol esters (40-60% total). 

The association of chitin, D-glucan, and D-mannan in the cell walls of Candida albicans and the spatial distribution of these polysaccharides have been found to vary appreciably between two dimorphs and with the age of the culture. ... 

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