CambridgeSoft

NCI Database - Over 200,000 compounds with anti-cancer drug dose-response data. 

AIDS Database - NCI compiled database for AIDS anti-viral compounds. ChemINDEX 9.0 - Small molecule physical property data on over 70,000 compounds. 

ChemRXN 9.0 - Organic reaction databases include ChemSelect from Infochem GmbH and a selection from ISI s ChemPrep, for a total of over 29,000 reactions. 

ChemDraw ActiveX/Plugin Pm 9.0 allows one to query online databases and view and publish online structures. 

The Merck Index 13th CD-ROM Edition is an encyclopedia of chemicals, drugs and biologicals with over 10,000 monographs on single substances or groups of related compounds. 

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The MOPAC program of CambridgeSoft webpage http //www.camsoft.com... 

Early implementations of the CIP rules for computer detection and specification of chirality were described for the LHASA [105], CHIRON [106], and CACTVS [107] software packages. Recently, several commercial molecular editors and visualizers (e.g., CambridgeSoft s ChemOffice, ACD s I-Lab, Accelrys WebLab, and MDL s AutoNom) have also implemented the CIP rules. 

Price category student, individual, production Platforms PC (Windows), Macintosh Contact information CambridgeSoft 100 Cambridge Park Drive Cambridge, MA 02140 (617) 588-9300 http //www.camsoft.com/ info camsoft.com... 

In 1999 CambridgeSoft released a desktop/personal version of an e-notebook, specifically targeted at medicinal chemistry this incorporated reaction drawing and searching, automatic stoichiometry calculations, and simple procedure write-up using plain text. This system was adopted both by individuals, particularly in the academic community, and by small and mediumsized companies as an alternative to building an in-house hybrid system (Fig. 9.2). 

Alfred Nehme, CambridgeSoft Corporation, 100 Cambridgepark Drive, Cambridge, MA 02140, USA. (anehme cambridgesoft.com). 

Robert A. Scoffin, CambridgeSoft Corporation, 8 Signet Court, Swann s Road, Cambridge, CB5 SLA, UK. (rscoffin cambridgesoft.com). 

CambridgeSoft at http //www.cambridgesoft.com/products offers a variety of tools including the software suite, ChemOffice . The combination package consists of ChemDraw , Chem3D , and ChemFinder . Every undergraduate... 

Figure 2.10 Secondary and tertiary structure of the enzyme lysozyme, PDB 2C80. Visualized using Cambridge Soft Chem3D Ultra 10.0 with notations in ChemDraw Ultra 10.0. ChemDraw Ultra, version 10.0. (Printed with permission of CambridgeSoft...

Figure 2.22 Zinc-finger-DNA interactions for PDB IZAA as described in reference 31 and the text. Visualized using The PyMOL Molecular Graphics System and Chem-Draw Ultra, version 10.0. (Printed with permission of Delano Scientific, LLC and CambridgeSoft Corporation.) (See color plate)...

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