Calcimar

Calcia [1305-78-8] Calci-Bind Calcimar Calcimycin [52665-69-7] Calcination Calcined gypsum Calcined limestone... 

Calcitonin. Calcitonin is available commercially from pork and salmon extracts (Calcimar, Armour) as well as by synthesis. Preparations are bioassayed on the basis of their calcium-lowering activity in comparison to the potency of pure pork calcitonin of which ca 4 p.g is equivalent to 1 MRC unit (Medical Research Council, U.K.). For clinical use, vials containing 400 units in 4 mL are available. The recommended daily dosage is 100 units to be adrninistered subcutaneously or intramuscularly because its plasma half-life is short (4—12 min). 

Calcitonin is also effective in reducing serum calcium levels in life-threatening hypercalcemia however, it is not as rapid or as effective as the bisphosphonates. Subcutaneous administration of salmon (Calcimar) or human (Cibacalcin) calcitonin reduces serum calcium levels within 3 to 5 days in 75 to 90% of malignant hypercalcemias. 

Brand Name(s) Calcimar, Cibacalcin, Fortical, Miacalcin, Miacalcin Nasal CfiemicalClass Polypeptide hormone... 

Calcitonin has proved useful as ancillary treatment in a large number of patients. Calcitonin by itself seldom restores serum calcium to normal, and refractoriness frequently develops. However, its lack of toxicity permits frequent administration at high doses (200 MRC units or more). An effect on serum calcium is observed within 4-6 hours and lasts for 6-10 hours. Calcimar (salmon calcitonin) is available for parenteral and nasal administration. 

Parenteral (Calcimar, Miacalcin, Salmonine) 200 IU/mL for injection Cinacalcet (Sensipar)... 

Calcitonin Human calcitonin (Cibacalcin) Salmon calcitonin (Calcimar, Miacalcin) Mimic the effects of endogenous calcitonin and increase bone formation in conditions such as Paget disease and osteoporosis also used to lower plasma calcium levels in hypercalcemic emergencies... 

Hence, calcitonin has emerged as an effective and easy way to treat a variety of conditions that are characterized by increased bone resorption.59,82 Calcitonin preparations used clinically are either identical to the human form of this hormone (Cibacalcin) or chemically identical to salmon calcitonin (Calcimar, Miacal-cin). Redness and swelling may occur locally when these agents are administered by injection. Other side effects include gastrointestinal disturbances (stomach pain, nausea, vomiting, and diarrhea), loss of appetite, and flushing or redness in the head, hands, and feet. 

Trade names Calcimar (Sanofi-Aventis) Caltine Cibacalcine Clasynar Miacalcic Miacalcin (Novartis)... 

Bromurex pancuronium calcitonin Calcimar, Caltine, Cibacalcine, Clasynar, Miacalcic,... 

Calcitonin (calcimar, miacalcin) can rapidly reduce Ca, but the response is generally transient and the magnitude of response is less than with other agents. The recommended stating dose is 4 U/kg administered subcutaneously every 12 hours if there is no response within 1 or 2 days, the dose may be increased to 8 U/kg every 12 hours, or then to a maximum of 8 U/kg every 6 hours. 

Calcitonin (Calcimar [IV, SC] Miacalcin and Fertical [nasal spray])... 

The client with postmenopausal osteoporosis is prescribed calcitonin (Calcimar) intranasal. Which instructions should the nurse discuss with the client ... 

Which statement best describes the scientific rationale for administering calcitonin (Calcimar) to a client diagnosed with osteoporosis ... 

Calcimar is a natural product obtained from salmon and is approved for treatment of osteoporosis in women who are more than 5 years postmenopause. It increases bone density and reduces the risk of vertebral fractures. 

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