Keratopathy calcific band

Acute-onset calcific band keratopathy has been reported in a woman using topical prednisolone (SEDA-20, 372 75). 

Rao GP, O Brien C, Hicky-Dwyer M, Patterson A. Rapid onset bilateral calcific band keratopathy associated with phosphate-containing steroid eye drops. Eur J Implant Refractive Surg 1995 7 251-2. 

Anaphylactoid keratitis Allergic contact keratitis Irritative or toxic keratitis Phototoxic keratitis Toxic calcific band keratopathy Pseudotrachoma Cumulative deposition Microbial imbalance... 

Steroid-indnced calcinm deposits in the cornea have been reported. Patients with such persistent epithelial defects snch as postoperative inflammation, penetrating keratoplasty, and a history of herpetic keratitis and dry eye have developed a calcific band keratopathy after topical nse of a steroid phosphate formnlation. 

P.S. Binder, J.K. Deg, and F.S. Kohl. Calcific band keratopathy after intraocular chondroitin sulfate. Arch. 

In the early stages the patient with band keratopathy remains asymptomatic. However, once the calcification extends into the visual axis, the patient reports decreased visual acuity, visual halos, or a white spot on the eye.The accumulation of calcium can result in disruption of the normal ocular surface, resulting in irritation, photophobia, or RCEs.A patient who develops band keratopathy in a non-seeing eye may be asymptomatic for this condition. 

The major effects of hyperphosphatemia are related to the development of hypocalcemia (caused by phosphate inhibition of renal la-hydroxylase) and its related consequences, as well as vascular and organ damage resulting from the deposition of calcium-phosphate crystals. Extravascular calcification can result in band keratopathy, red eye, pruritus, and periarticular calcification, especially in renal failure patients (see Chap. 44). In addition, soft-tissue calcifications in the conjunctiva, skin, heart, cornea, lung, gastric mucosa, and kidney have been observed, primarily in chronic renal failure patients." Hyperphosphatemia associated with chronic renal disease may result in renal osteodystrophy because of overproduction of parathyroid hormone. This condition is discussed in detail in Chap. 44. 

J.W. Cursino and B.S. Fine. A histologic study of calcific and noncalcific band keratopathies. Am. J. 

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