Caffeine gastrointestinal system effects

Coffee causes nervousness, tremors, insomnia, and gastric symptoms withdrawal symptoms —With excessive coffee intake, some individuals develop untoward nervous system effects from caffeine, such as nervousness, tremors, and insomnia. In rare cases, there may be gastric symptoms such as heartburn, abdominal discomfort, or diarrhea but generally such gastrointestinal effects occur with excessive coffee consumption. Also, some experience headaches with the withdrawal of caffeine, beginning about 12 to 15 hours after the last dose of caffeine. 

Caffeine is a powerful stimulant of central nervous system and also stimulates the cardiac muscle. However, high amounts of the alkaloid have noticeable irritation of gastrointestinal tract as well causes matw unwanted effects [1]. 

Caffeine is a stimulant of the central nervous system. It eliminates fatigue and drowsiness. However, high doses cause gastrointestinal motility, restlessness, sleeplessness, nervousness, and tremor. Acute poisoning effects include nausea, vomiting, headache, excitability, tremor, and sometimes, convulsive coma. Other symptoms may be respiratory depression, muscle contraction, distorted perception, and hallucination. Ingestion of 15-20 g may be fatal to humans. 

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