Caenorhabditis elegans effects

Golden, J.W. and Riddle, D.L. (1984) The Caenorhabditis elegans dauer larva developmental effects of pheromone, food, and temperature. Developmental Biology 102, 368—378. 

Donkin, S.G. and D.B. Dusenbery. 1993. A soil toxicity test using the nematode Caenorhabditis elegans and an effective method of recovery. Arch. Environ. Contam. Toxicol. 25 145-151. 

For large-scale analysis, this strategy has been further modified for use in the array method (Ito et al., 2000 Uetz et al., 2000 Walhout et al., 2000). Such analyses in Sachromyces cerevisiae and Caenorhabditis elegans have already reported many potential interactions that need to be confirmed by further biological experimentation. Finally, another modification of the yeast two-hybrid system has been recently reported, termed reverse two-hybrid (Vidal and Endoh, 1999). This technique is being used to identify compounds and peptides that can disrupt protein-protein interactions and thus have an effect on various signaling pathways. 

Hoss, S. and Krebs, F. (2003) Dilution of toxic sediments with unpolluted artificial and natural sediment - Effects on Caenorhabditis elegans (Nematoda) in a whole sediment bioassay -Proceedings 13th Annual meeting, Society of Environmental Toxicology and Chemistry - Europe Branch (SETAC-Europe), 28.04 -01.05. 2003, Hamburg, pp. 148. 

Jonker MJ. 2003. Joint toxic effects on Caenorhabditis elegans on the analysis and interpretation of mixture toxicity data [PhD thesis]. Wageningen (The Netherlands) Wageningen University and Research Centre. 

Jiang, G.C., Tidwell, K., McLaughlin, B.A., Cai, J., Gupta, R.C., Milatovic, D., Nass, R., Aschner, M. (2007). Neurotoxic potential of depleted uranium effects in primary cortical neuron cultures and in Caenorhabditis elegans. Toxicol. Set 99 553-65. 

Kamath RS, Martinez-Campos M, Zipperlen P, Fraser AG, Ahringer J (2001) Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans. Genome Biol 2(1) RESEARCH0002... 

Pyrene is metabolized by the fungus Crinipellis stipitaria to 1-hydroxypyrene, and this has a spectrum of toxic effects substantially greater than those of pyrene these include cytotoxicity to HeLa S3 cells, toxicity to a number of bacteria and to the nematode Caenorhabditis elegans (Lambert et al. 1995). 

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