C Production of Gluconic Acid by Aerobic

Reuss et al. [1986] modeled this process on the basis of a careful experimental program. The kinetics of gluconic acid production were described by means of the Michaelis-Menten equation (Section 1.5.1 of Chapter 1). At a pH of 5.6 the constant Km in that equation amounted to 0.36 mmol/h and the specific oxygen uptake rate (half of the specific production rate, yp) 65 mol oxygen per kg dry weight and per hour. 

The production rate is intrinsically very fast but limited by the oxygen uptake of the liquid. The volumetric oxygen transfer coefficient Az,a was also affected by the increasing viscosity of the medium as the amount of biomass increased. 

Using the definitions and symbols of microbial kinetics the model equations can be written  

X represents the biomass, P the product, and 5 the glucose (or substrate) concentration (kg/m ). For a clear insight into the first equation in particular it is useful to remember that p is the specific biomass growth rate in h (see Section 

Comparison between on-line computer estimatiois (solid lines) and laboratory mesurements ( biomass, o— subcinte, a — product) 

---

Example 8.1.B Styrene Polymerization in a Batch Reactor Example 8.1.C Production of Gluconic Acid by Aerobic Eermentation of Glucose... 

---