C palladium-catalyzed

C. Palladium-catalyzed reactions with oxygen nucleophiles. 

Zhou, J. Fu, G. C. Palladium-catalyzed Negishi cross-coupling reactions of unactivated alkyl iodides, bromides, chlorides, and tosylates. I. Am. Chem. Soc. 2003, 125, 12527-12530. 

The construction of -silyl divinyl ketones in many different structural settings has been weU developed. The four principal connections outlined in Scheme 16 are as follows path a, vinyl organome-tallic addition to 3-trimeAylsilyl-2-propenal path b, 3-trialkylsilylvinyl organometallic" addition to enals path c, palladium-catalyzed carbonylation/coupling of 2-trimethylsilylvinyltrimethylstan-nane and path d, acylation of a B-silyl copper reagent. 

Larock, R. C. Palladium-catalyzed annulation. PureAppl. Chem. 1999, 71,1435-1442. 

Negishi, E.-i., Xu, C. Palladium-catalyzed alkynylation with alkynylmetals and alkynyl electrophiles. Handbook of Organopalladlum Chemistry for Organic Synthesis 2002, 1, 531-549. 

NuH = Alcohols, phenol, and amines Scheme 1.22 (a-c) Palladium-catalyzed carbonylative synthesis of indoles and thiophenes. 

More recently, Dong s group developed a palladium-catalyzed synthesis of indoles from nitroalkenes [43]. This was the first report on transition metal-catalyzed transformation of conjugated nitroalkenes into indoles. Under mild reaction conditions (1 bar carbon monoxide, 110 °C), palladium catalyzes the reductive cyclization of nitroalkenes to form a putative nitrosoalkene intermediate, which then rearranges to provide 3-arylindoles in high yields (Table 9.5). Notably, this novel C-H bond amination takes advantage of carbon monoxide as an inexpensive stoichiometric reductant and produces carbon dioxide as the major byproduct. 

C. PALLADIUM-CATALYZED HYDROGENOLYSIS WITH OTHER HYDRIDE SOURCES... 

C. PALLADIUM-CATALYZED REDUCTIONS WITH GROUP 14 METAL HYDRIDES... 

B.i.c. Palladium-Catalyzed Hydrosilation ofAlkynes. Relatively little has been reported on the Pd-catalyzed hydrosilation of alkynes. This is in sharp contrast with the corresponding hydrostannation of alkynes discussed later in Sect. C. The reaction of terminal alkynes with HSiEts in the presence of polyborane-containing Pd and Pt complexes yielded the results summarized in Scheme 10, which indicate that Pd and Pt catalysts... 

C. PALLADIUM-CATALYZED OR -PROMOTED OXIDATION OF ARENES PRODUCING ACETOXYARENES... 

C. PALLADIUM-CATALYZED CLEAVAGE OFF THE SOLID SUPPORT AND CONCOMITANT DERIVATIZATION... 

C. Palladium-Catalyzed Cyclization Reactions of Acetylene Containing Amino Acids... 

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