Butyl a-hydroxypropionate

SYNS BUTYL a-HYDROXYPROPIONATE BUTYL LACTATE 2-HYDROXYPROPANOIC ACID, BUTYL ESTER LACTIC ACID, BUTYL ESTER... 

BUTYLHYDROXYOXOSTANNANE see BSL500 BUTYL a-HYDROXYPROPIONATE see BRR600 BUTYLHYDROXYTOLUENE see BFW750 BUTYLIDENE PHTHALIDE see BRQIOO... 

Synonyms butyl a-hydroxypropionate propanoic acid 2-hydroxy butyl ester lactic acid butyl ester Purasolv BL. Boiling point 188°C Melting point —43°C... 

BUTYL-a-HYDROXYPROPIONATE (138-22-7) Combustible liquid (flash point 160°F/71°C). Incompatible with strong oxidizers, strong ba.ses. 

Synonyms Butyl 2-hydroxypropanoate Butyl a-hydroxypropionate n-Butyl-S(-)-2-hydroxypropionate n-Butyl lactate 2-Hydroxypropanoic acid butyl ester Lactic acid butyl ester Propanoic acid, 2-hydroxy-, butyl ester Classirication Ester Empirical CjHuOs Fomiula CH3CHOHCOOC4H,... 

Bupropion hydroxylation of the tert-butyl group to hydroxypropion is mediated almost exclusively by CYP2B6 and, to a lesser extent, by CYP2E1 (74). Other metabolites include reduction of the aminoketone to amino-alcohol isomers, threo-hydrobupropion and erythro-hydrobupropion (Fig. 21.21). Further oxidation of the bupropion side chain results in the formation of m-chlorobenzoic acid, which is eliminated in the urine as its glycine conjugate. Hydroxybupropion is approximately 50% as potent as bupropion, whereas threo-hydrobupropion and erythro-hydrobupropion have 20% of the potency of bupropion. Peak plasma concentrations for hydroxybupropion are approximately 10 times the peak level of the parent drug at steady state, with an elimination half-life of approximately 20 hours. The times to... 

Acrylic acid is an important chemical building block used in the manufacture of polyacrylates and commodity acrylates. Commodity acrylates, such as methyl, ethyl, n-butyl, and 2-ethylhexyl acrylate, are utilized in various industrial applications, including coatings, adhesives and sealants, textiles and fibers, polymer additives/impact modifiers, and films. Polyacrylates are extensively used as super absorbent polymers. Bio-based acrylic acid can be obtained through the fermentation of carbohydrates to 3-hydroxypropionic acid (3-HPA), and further dehydration of 3-HPA gives acrylic acid. 3-HPA could also be used as a precursor to other important chemical building blocks, such as PDO, acrylonitrile, and acrylamide. Via another route, glycerol can be chemically converted to acrylic acid, either by dehydration to acrolein followed by oxidation to the final product or in a one-step oxydehydration. 

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