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Glycine conjugation

Glycine conjugation Carboxylic acids Acyl-CoA amino acid N-transferase Glycinamide conjugates... [Pg.173]

Free and glycine-conjugated BAs are only slightly soluble in acid solutions. As the pH is increased, the solubility will increase. This is a very important characteristic since it describes the solubility characteristics of the major BAs, and, it also explains their potential to enter the epithelium at physiological pH ranges. [Pg.9]

Other drugs are metabolised by Phase II synthetic reactions, catalysed typically by non-microsomal enzymes. Processes include acetylation, sulphation, glycine conjugation and methylation. Phase II reactions may be affected less frequently by ageing. Thus according to some studies, the elimination of isoniazid, rifampicin (rifampin), paracetamol (acetaminophen), valproic acid, salicylate, indomethacin, lorazepam, oxazepam, and temazepam is not altered with age. However, other studies have demonstrated a reduction in metabolism of lorazepam, paracetamol (acetaminophen), ketoprofen, naproxen, morphine, free valproic acid, and salicylate, indicating that the effect of age on conjugation reactions is variable. [Pg.207]

Glycine conjugation Glycine Acyl-CoA glycinetransferase (mitochondria) Acyl-CoA derivatives of carboxylic acids Salicylic acid, benzoic acid, nicotinic acid, cinnamic acid, cholic acid, deoxycholic acid... [Pg.85]

Kumps A, Vamos E, Mardens Y, Abramowicz M, Genin J, Duez P (2004) Assessment of an electron-impact GC-MS method for organic acids and glycine conjugates in amniotic fluid. J Inherit Metab Dis 27 567-579... [Pg.168]

Free bile acids Glycine conjugates Taurine conjugates... [Pg.608]

Standard solutions of free BAs and of glycine-conjugated Bas are employed for the calibration. In the cited work the following concentration ranges were used 0.47-... [Pg.626]

See other pages where Glycine conjugation is mentioned: [Pg.270]    [Pg.430]    [Pg.264]    [Pg.267]    [Pg.220]    [Pg.67]    [Pg.201]    [Pg.116]    [Pg.339]    [Pg.139]    [Pg.169]    [Pg.170]    [Pg.417]    [Pg.557]    [Pg.146]    [Pg.3]    [Pg.3]    [Pg.9]    [Pg.9]    [Pg.10]    [Pg.10]    [Pg.11]    [Pg.113]    [Pg.255]    [Pg.123]    [Pg.167]    [Pg.174]    [Pg.185]    [Pg.1383]    [Pg.325]    [Pg.329]    [Pg.342]    [Pg.247]    [Pg.248]    [Pg.249]    [Pg.40]    [Pg.608]    [Pg.611]    [Pg.623]    [Pg.626]   
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See also in sourсe #XX -- [ Pg.354 , Pg.356 , Pg.397 ]



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Benzoic acid conjugation with glycine

Bile Conjugation, Glycine

Biotransformation processes glycine conjugation

Conjugate glycine imine esters

Free and glycine conjugated

Glycine conjugate

Glycine conjugate

Glycine conjugated bile salts

Glycine conjugation with

Glycine conjugation, species

Glycine, reactions conjugate addition

Glycine-Conjugated BAs

Glycine-conjugated bile acids

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