Bruice, Thomas

Proximity Effects and Enzyme Catalysis Thomas C. Bruice... 

A good fraction of modern chemistry, which includes medicinal chemistry, derives some of its inspiration from a consideration of nature as a model. It is impossible, in this brief article, to describe more than a fraction of the efforts. For additional work in the spirit of biomimetic chemistry, the following is a list of some authors not yet mentioned whose independent work should be consulted. Even here, this list is certainly not complete Jacqueline Barton, Steven Benkovic, Albrecht Berkessel, Thomas Bruice, Jik Chin, Jean Chmielewski, E. J. Corey, Donald Cram, Peter Dervan, Erancois Diederich, Mark Distefano, Jean Frechet, Samuel Gelhnan, John Groves, Andrew Hamilton, Donald Hilvert, Barbara Imperiali, Makoto Komiyama, Jean-Marie Lehn, Arthur Martell, Julius Rebek, Jean-Pierre Sauvage, Alanna Schepartz, Dieter Seebach, Donald Tomalia, and Steven Zimmerman. 

Professor Thomas C. Bruice (University of California, Santa Barbara) Dr. James Fee (Los Alamos National Laboratory)... 

Edmond Y. Lau, Kalju Kahn, Paul A. Bash and Thomas C. Bruice, The importance of reactant positioning in enzyme catalysis a hybrid quantum mechanics/molecular mechanics study of a haloalkane dehalogenase, Proceedings of the National Academy of Sciences USA, 97 (2000), 9937-9942. 

Seiji Shinkai was born in 1944 in Fukuoka, Japan, and received his PhD in 1972 from Kyushu University, where he became a lecturer soon afterwards. After postdoctoral work at the University of California, Santa Barbara, with Thomas C. Bruice, he joined Kyushu University in 1975 and became a full... 

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