Bromochlorodifluoromethane

Various bromofluoromethanes have been described and proposed for use as fire extinguishing agents (qv). Two that have been recommended highly for this purpose are dibromo difluoromethane [75-61-6] CBr2p2, and bromotrifluoromethane [75-65-8], CBrF, (94). Bromochlorodifluoromethane [353-59-3], CBrClF2, is another fire extinguishing agent. These and similar substituted methanes are potentially useful for the synthesis of other halo—fluoro compounds. 

Bromobenzene Bromochlorodifluoromethane Bromochloromethane 1 -Bromo-2-chloropropane Bromoethane... 

Condensation of dibromodifluoromethane or bromochlorodifluoromethane with potassium phenoxides usually needs an initiation by a thiol and occurs by an ionic chain mechanism [/5, 16 (equations 14 and 15)... 

Alkylation of thiolate anions by bromochlorodifluoromethane generally follows this mechanism [55, 57] However, depending on the nature of the nucleophile and reaction condibons, disubstimtion can arise by a SET process [57] (equation 49)... 

A similar distribution of copper reagents can be obtained via the du ect reaction of copper metal with dibromodifluoromethane or bromochlorodifluoromethane in DMF at 85-95 °C [2J2] The oligomerization can be supressed via the addition of alkali metal fluorides to the reaction mixture [272] When HMPAis added to the trifluoromethylcopper solution, decomposition is slowed, and this solution can be used to trifluoromethylate aromatic iodides [270] (equation 143). 

The unique combination of properties associated with certain fluonnated methanes and ethanes has led to their widespread use in fire suppression systems The three halogenated fire suppression agents in general use today are bromo-trifluoromethane (CF Br, Halon 1301), bromochlorodifluoromethane (CF2BtCl, Halon 1211) and, in small volumes, primarily in the republics of the former Soviet Union and Eastern European nations, 1,2-dibromotetrafluoroethane (BrCF2Cp2Br, Halon 2402)... 

FLUORINECOMPOUNDS,ORGANIC - FLUORINATED ALIPHATIC COMPOUNDS] (Vol 11) Bromochlorodifluoromethane [353-59-3]... 

Qualitative work on the pyrolysis of bromochlorodifluoromethane, either pure or mixed with 1 1 air, at 400-800 °C showed it to proceed, as expected, through a complex free radical type mechanism140. The overall reaction yielded the products described in equation 57 ... 

The term glue-sniffing derives from the abuse of adhesives which often contain solvents such as toluene, ethyl acetate, acetone, or ethyl methyl ketone. These, and similar compounds, also occur in a diverse range of other commercial products which may be abused, e.g. shoe-cleaners, nail varnish, dry-cleaning fluids, bottled fuel gases (butane and propane), aerosol propellents, and fire extinguishers (bromochlorodifluoromethane). 

Grobe and Hegge demonstrated that aluminum powder in fV-methylpyrrolidinone (NMP) can also be used for the reduction of bromotrifluoromethane in the presence ofchlorotrimethyl-silane to produce trimethyl(trifluoromethyl)silane, a method more convenient than the modified Ruppert procedure. The C Br bond of bromochlorodifluoromethane is selectively reduced by aluminum powder in. V-methylpyrrolidinone in the presence of ehlorotrimethylsilane giving (chlorodifluoromethyl)trimethylsilane in 80% isolated yield. The process appears to involve a two-electron reduction of the C Br bond of bromochlorodifluoromethane followed by trapping of the resulting CFjCU" anion by chlorotrimethylsilane. Aluminum powder, corresponding to a net consumption of two electrons per mole of bromochlorodifluoromethane. is needed for the reduction. 

BROMOCARBAiSnDE see BNP750 BROMOCHLORODIFLUOROMETHANE see BNA250 7-BROMO-6-CHLOROFEBRIFUGINE HYDROBROMIDE see HAF600 7-BROMO-6-CHLORO-3-[3-(3-HYDROXY-2-PIPERDINYL)-2-OXOPROPYL]-4(3H)-QUINAZOUNONE HYDROBROMIDE see HAF600... 

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