Bridges binder

In both cases, finely divided binder is added in a suitable manner to the turbulently agitated mass of particles. If solid particles are suspended in a liquid, agglomerates may be formed after adding a second, immiscible bridging (binder) liquid - immiscible binder a lomeration (see also Section 7.4.6). In the widest sense, this technology belongs to the Type Il-processes. 

Initial macrocyclic analogs showed enhanced potency relative to non-cyclic precursors and subsequent lead optimization of the linker, salt-bridge binder (to an acylsulfonamide), and aiyl substituents led to the identification of candidate TMC647055 (Figure 7 14) so,100,101 17-membered macrocyclic... 

Baschnagei, /., Binder, K, Doruker P., Gusev, A, A., Hahn, O., Kremer, K, Matt ice, W. L MUUer-Plathe, K, Murat, AL, Paul, W., Santos, S Sutter, U. IV, Dries, V, Bridging the Gap Between Atomistic and Coarse-Grained Models of Polymers Status and Perspectives. VoL 152, pp. 41-156. 

Critical Binder Liquid/Powder Ratio. When a liquid is mixed into a bulk powder made of fine particles, the liquid distributes itself first into small spaces between particles forming liquid bridges as can be seen in Fig. 12a. For very small amounts of liquid, these bridges are randomly spaced and do not influence the bulk properties of the powder. Upon introduction of larger... 

A typical plot of torque versus amount of liquid (di-butyl-phthalate, DBT) added is given in Fig. 15 for a very porous sodium carbonate powder mixture. The increase in measured torque at around 25% by volume DBT and again at around 65 %, can easily be seen (the final decrease in torque upon the formation of the wet cake is not shown). These two points correspond to the condition under which the continuous network of bridges forms, at about 25% liquid present, and the formation of the dry paste, at around 65%, where enough binder is available to fill most internal voids. The amount of liquid in Fig. 15 is given as a fraction of the total volume of powder, instead... 

Conditions of Coalescence. The outcome of the collision of two binder-covered particles is determined by the ratio of the initial kinetic energy of the system and the energy dissipated in the liquid bridge and in the particles. This can be expressed analytically by the definition of a so called Stokes number, St... 

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