Breast cancer detection, optical

Mammograms are uncomfortable and embarrassing for women. NIR imaging [84] and an optical biopsy [85] may be performed. NIR radiation has been suggested as an alternative to both x-rays and physical, invasive biopsies. Breast cancer is one of the leading causes of death and disfigurement in woman, it is best detected early [85]. 

Finally, in optical-based sensors and assays, there is the development of label-free bioanalytic detection on prepared membrane surfaces, ultra sensitive detection of microbial agents, the development of fiber-optic based enzyme sensors, multi-analyte breast cancer immunoassays, and photodynamic therapy of osteosarcoma in veterinary patients. 

Salama, O., Herrmann, S., Tziknovsky, A., et al., 2007. Chemiluminescent optical fiber immunosensor for detection of auto antibodies to ovarian and breast cancer-associated antigens. Biosens. Bioelectron. 22, 1508-1516. 

Luminescent magnetic materials. They can be useful in combined detection and separation in bioanalytical assays. For instance, polymer coated 7-Fe203 cores and CdSe/ZnS shells with immobilized anticycline E antibodies have been used for the separation and observation of MCF-7 breast cancer cells. " Materials joining potentially tunable optical and magnetic properties have been proposed that are composed of three-dimensional binary superlattices of self-assembled 7-Fe20j and PbSe nanoparticles. ... 

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